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5-Amino-1MQ: uses, dosing & the facts
5-Amino-1-methylquinolinium, a research compound that inhibits nicotinamide N-methyltransferase (NNMT), potentially increasing NAD+ levels and supporting metabolic health. This is an evidence-graded reference — what it is, what it's used for, typical reported dosing, half-life, side effects, and how to track it. It is educational, not medical advice or a recommendation to use a research compound.
- • 5-Amino-1MQ — Fat loss. 5-Amino-1-methylquinolinium, a research compound that inhibits nicotinamide N-methyltransferase (NNMT), potentially increasing NAD+ levels and supporting metabolic health.
- • Commonly used for nad+ level support, metabolic health, energy enhancement.
- • Half-life: Approximately 4-6 hours.
- • Status: Research use only · not FDA-approved — an educational reference, not a dose protocol or sourcing advice.
What 5-Amino-1MQ is
5-Amino-1-methylquinolinium, a research compound that inhibits nicotinamide N-methyltransferase (NNMT), potentially increasing NAD+ levels and supporting metabolic health.
What 5-Amino-1MQ is used for
- • NAD+ level support
- • Metabolic health
- • Energy enhancement
- • Potential anti-aging benefits
- • Weight management support
- • Metabolic syndrome research
These are reported/community uses, not proven clinical outcomes. Most research peptides have limited human trial data behind such claims.
Typical reported dosing
| Oral | 25-150mg taken orally daily with food |
| Injectable | Conservative start: 150mcg SubQ once daily (or 50-150mcg daily when stacked with oral/NAD+ protocols). Experienced users often ramp 1mg → 2.5mg, then 5mg daily; aggressive cutting logs report 7.5-10mg daily on 5-on/2-off rotations. |
Presented as commonly-reported patterns for information only — not a dose recommendation. 5-Amino-1MQ dosing is a decision for a qualified clinician.
Half-life & cycling
Half-life: Approximately 4-6 hours. Half-life drives dosing frequency and how quickly the compound clears — see it plotted on the half-life visualizer.
Cycling
Can be used continuously or in cycles. Typical cycles: 8-12 weeks on, 4 weeks off; higher-dose SubQ blocks usually follow 5-days-on / 2-days-off rhythms for 6-8 weeks.
Side effects & warnings
- • Generally well-tolerated
- • Possible mild gastrointestinal upset
- • Limited long-term safety data
Research use only. Human data are limited and injectable preparations require sterile technique. Start with microgram-level dosing before considering multi-milligram ramps; 5-10mg daily is generally not recommended for beginners. Oral administration remains simpler and may synergize with NAD+ supplementation. Not technically a peptide but often grouped with research peptides.
Tracking 5-Amino-1MQ in OptiPin
If you're tracking a 5-Amino-1MQ protocol, OptiPin logs each dose with reminders and site rotation, charts the outcome you care about over your dose timeline, keeps per-vial inventory with runout warnings, and (where relevant) does the reconstitution math — all on-device, no account.
Log doses, outcomes & vials in OptiPin
Reminders, outcome-over-dose charts, vial runout warnings, and built-in reconstitution math — all on-device.
Download on the App StoreFAQ
What is 5-Amino-1MQ?
5-Amino-1-methylquinolinium, a research compound that inhibits nicotinamide N-methyltransferase (NNMT), potentially increasing NAD+ levels and supporting metabolic health.
What is 5-Amino-1MQ used for?
Commonly discussed uses include: nad+ level support, metabolic health, energy enhancement, potential anti-aging benefits, weight management support, metabolic syndrome research. These are reported uses, not proven outcomes or a recommendation.
How is 5-Amino-1MQ dosed?
Commonly reported dosing: Oral — 25-150mg taken orally daily with food; Injectable — Conservative start: 150mcg SubQ once daily (or 50-150mcg daily when stacked with oral/NAD+ protocols). Experienced users often ramp 1mg → 2.5mg, then 5mg daily; aggressive cutting logs report 7.5-10mg daily on 5-on/2-off rotations.. This reflects patterns discussed in the community and is presented for information only, not as a dose recommendation — 5-Amino-1MQ is not an approved medicine and dosing should involve a qualified clinician.
What is 5-Amino-1MQ's half-life?
Approximately 4-6 hours. Half-life shapes how often it is dosed and how quickly it clears.
What are 5-Amino-1MQ's side effects?
Reported effects include: generally well-tolerated, possible mild gastrointestinal upset, limited long-term safety data. Because it is a research compound, its safety profile is not fully characterized; discuss risks with a clinician.
Evidence & further reading
- Search the peer-reviewed literature for 5-Amino-1MQ on PubMed (entry point to the primary evidence base, not a specific citation).
- 5-Amino-1MQ on ClinicalTrials.gov — registered human trials, if any.
- US FDA / 503A compounding status of research peptides (2026).
- OptiPin peptides guide — categories, evidence grading, and how to run a protocol honestly.
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