OptiPin
OptiPin
Comprehensive reference for 210+ medications tracked in OptiPin - TRT esters, GLP-1 agonists (semaglutide, tirzepatide, retatrutide), growth & recovery peptides, fat-loss and longevity compounds, and more. Educational only; consult a licensed provider before use.
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Every compound in the OptiPin library, with its half-life and a typical reported dose. Educational reference only — dosing is set by a licensed prescriber, not by this table. Use the search and filters above to open the full card for any entry.
| Compound | Half-life | Typical reported dose |
|---|---|---|
| Clomid (Clomiphene Citrate) | Approximately 5-7 days | 25-50mg daily or every other day. Typical PCT protocol: 50mg daily for 4-6 weeks. (oral) |
| DHT | Approximately 50-60 minutes | 25-50mg 2-3x per week IM. Start low and increase gradually. (injectable) |
| DHT Enanthate | Approximately 5-7 days | 5-40mg weekly, split into 1-2 injections IM. Typical dose: 10-20mg weekly. Start low and increase gradually. (injectable) |
| DHT Propionate | Approximately 1-2 days | 1-20mg every other day or 2-3x per week IM. Typical dose: 5-10mg every other day. Start low and increase gradually. (injectable) |
| DIM (Diindolylmethane) | Approximately 3-4 hours | 100-300mg daily with food. Start at 100mg and increase as needed. (oral) |
| Enclomiphene | Approximately 24 hours | 12.5-25mg daily. Typical dose 12.5mg daily or every other day. Titrate based on response and bloodwork. (oral) |
| Estrogen Blocker (Anastrozole) | Approximately 50 hours | 0.25-1.0mg every other day or 2-3x per week. Start low and adjust based on bloodwork. (oral) |
| Exemestane | Approximately 24 hours | TRT support: 6.25-25mg daily or every other day. Start low (6.25mg) and titrate based on bloodwork. (oral) |
| Gonadorelin | Approximately 10-15 minutes | 100-250mcg subcutaneously or intramuscularly, 2-3x per week (injectable) |
| hCG (Human Chorionic Gonadotropin) | Approximately 24-36 hours | Fertility (female only): 5,000-10,000 IU as single dose to trigger ovulation. Male fertility/TRT: 250-500 IU 2-3x per week. Weigh… |
| Testosterone Cypionate | Approximately 8 days | TRT: 50-200mg every 2-7 days IM or SubQ. Typical dose: 100-200mg weekly. (injectable) |
| Testosterone Decanoate | Approximately 15 days | TRT: 50-200mg every 3.5-14 days IM. Typical dose: 100mg every 3.5 days (twice weekly) or 200-400mg every 2-4 weeks. (injectable) |
| Testosterone Enanthate | Approximately 4.5 days | TRT: 50-200mg every 5-7 days IM or 2-3.5 days subcutaneously. Typical dose: 100-200mg weekly. (injectable) |
| Testosterone Gel | Varies, but provides daily dosing for stability | 25-100mg daily applied to clean, dry skin on shoulders, upper arms, or abdomen (topical) |
| Testosterone Isocaproate | Approximately 4-5 days | TRT: 50-150mg every 3-7 days IM or subcutaneously. Typical dose: 100-200mg every week. (injectable) |
| Testosterone Patch | Continuous delivery over 24 hours | 2-10mg patch applied to the back, abdomen, thigh, or upper arm daily (topical) |
| Testosterone Phenylpropionate | Approximately 4-5 days | Rarely used alone; in blends typically 50-100mg per injection. Standalone TRT: 50-100mg every 3-5 days IM. (injectable) |
| Testosterone Propionate | Approximately 19-20 hours | TRT: 50-100mg every 2-3 days IM or 1-2.5 days subcutaneously. Typical dose: 50mg every other day. (injectable) |
| Testosterone Sustanon | Blend; approximately 2-3 weeks effective duration | TRT: 250mg every 2-3 weeks IM, or 125mg every 1-2 weeks. Some protocols use 250mg weekly or split doses. (injectable) |
| Testosterone Undecanoate | Approximately 20-34 days (injectable) | 1000mg IM every 10-14 weeks (follow product labeling). Loading may involve two injections 4-6 weeks apart. (injectable) |
| Compound | Half-life | Typical reported dose |
|---|---|---|
| Albiglutide (Tanzeum) | Approximately 5 days | 30-50mg injected once weekly subcutaneously (injectable) |
| Dulaglutide (Trulicity) | Approximately 5 days | Start at 0.75mg weekly, can increase to 4.5mg weekly. Weekly subcutaneous injections. (injectable) |
| Exenatide (Byetta) | Approximately 2.4 hours | 5-10mcg injected twice daily, before morning and evening meals (injectable) |
| Exenatide Extended Release (Bydureon) | Approximately 5 days (extended release) | 2mg injected once weekly subcutaneously (injectable) |
| Liraglutide (Saxenda) | Approximately 13 hours | For weight loss: Start at 0.6mg daily, titrate to 3.0mg over 4-8 weeks. Daily injections subcutaneously. (injectable) |
| Lixisenatide (Adlyxin) | Approximately 3 hours | 10-20mcg injected once daily within 1 hour before first meal (injectable) |
| Mazdutide | Once-weekly dosing provides sustained effect | Weeks 1-4: 1-2mg/week (20-40 units). Weeks 5-8: 3-4mg/week (60-80 units) if tolerated. Weeks 9+: 4-6mg/week (80-120 units) for ma… |
| Orforglipron | Approximately 29-49 hours (very long) | Type 2 Diabetes: 3mg, 12mg, or 36mg daily. Weight Management: 12mg, 24mg, or 36mg daily (up to 12% body weight reduction over 72… |
| Retatrutide | Approximately 6-8 days (150-200 hours) | Weeks 1-4: 1mg once weekly (starting dose to assess tolerance). Weeks 5-8: 2mg once weekly (gradually increase if tolerated). Wee… |
| Semaglutide (Wegovy/Ozempic) | Approximately 1 week | Weeks 1-4: 0.25mg weekly. Weeks 5-8: 0.5mg weekly. Weeks 9-12: 1.0mg weekly. Weeks 13-16: 1.7mg weekly. Week 17+: 2.4mg weekly (m… |
| Survodutide | Approximately 5-7 days | Weeks 1-4: 0.6mg weekly. Weeks 5-8: 1.2mg weekly. Weeks 9-12: 2.4mg weekly. Weeks 13-16: 3.6mg weekly. Weeks 17+: 4.8mg weekly (m… |
| Tirzepatide (Mounjaro/Zepbound) | Approximately 5 days | Weeks 1-4: 2.5mg weekly. Weeks 5-8: 5mg weekly. Weeks 9-12: 7.5mg weekly. Weeks 13-16: 10mg weekly (if needed). Weeks 17-20: 12.5… |
| Compound | Half-life | Typical reported dose |
|---|---|---|
| Actovegin | Varies | 5-20mg injected intramuscularly or intravenously daily. Higher doses (20-40mg) used for acute conditions. Lower maintenance doses… |
| Anadrol | Approximately 8-9 hours | 25-150mg daily. Beginner: 25-50mg daily. Intermediate: 50-100mg daily. Advanced: 100-150mg daily. Usually run 4-6 weeks. (oral) |
| Anavar | Approximately 9-10 hours | Men: 20-80mg daily, typically split into 2 doses. Women: 5-20mg daily. Beginner: 20-40mg daily. (oral) |
| ARA-290 | Short; daily dosing is standard. | 2–4 mg subcutaneously once daily. Clinical trials have used 4 mg daily for 28 days; 2 mg daily is also common for maintenance or… |
| BPC-157 | 4-6 hours | 100-500mcg 1-2x daily, subcutaneously for 100-1000mcg total daily (injectable) |
| CJC-1295 (with DAC) | Approximately 6-8 days | 500-1000mcg per injection, 1-2 times per week. Total weekly dose: 1000-2000mcg, bodybuilders reportedly use up to 4000mcg weekly… |
| CJC-1295 (without DAC) | Approximately 30 minutes | 100-300mcg per injection, 1-3 times daily injected subcutaneously before bed on empty stomach (injectable) |
| Deca | Approximately 15 days | 200-600mg weekly, typically split into 1-2 injections. Beginner: 200-300mg weekly. Intermediate: 300-400mg weekly. Advanced: 400-… |
| DHB | Depends on ester (propionate approx 2 days; cypionate approx 6-8 days) | 300-500mg weekly (commonly as the propionate or cypionate ester). Beginner: 200-300mg/wk. Advanced: 400-500mg/wk. Dose split freq… |
| Dianabol | Approximately 4.5-6 hours | 10-50mg daily, typically split into 2-3 doses. Beginner: 10-20mg daily. Intermediate: 25-40mg daily. Advanced: 40-50mg daily. (or… |
| EQ | Approximately 14-16 days | 200-600mg per week IM, typically split into 1-2 injections. Common dose 400mg/week. Lower doses (200-300mg) for mild cycles. (inj… |
| GHRP-2 | Approximately 30 minutes | 100-200mcg injected subcutaneously 2-3x daily on empty stomach (injectable) |
| GHRP-6 | Approximately 20-30 minutes | 100-200mcg injected subcutaneously 1-3x daily on empty stomach (injectable) |
| GLP-2 | Approximately 7 minutes (very short) | 1-5mg injected subcutaneously daily (injectable) |
| Halotestin | Approximately 9 hours | 10-40mg daily. Beginner: 10mg daily. Intermediate: 20mg daily. Advanced: 30-40mg daily. Often used only in the final 2-4 weeks be… |
| Hexarelin | Approximately 20-30 minutes | 100-200mcg injected subcutaneously 1-2x daily on empty stomach (injectable) |
| HGH (Somatropin) | Approximately 3-4 hours | 1-4 IU daily injected subcutaneously in the morning or before bed. Typically no more than1-2 IU for longevity purposes. Advanced… |
| IGF-1 LR3 | Approximately 20-30 hours | Beginners: 20-50mcg daily post-workout. Intermediate/Advanced: 50-100mcg daily. Some split doses AM/PM. Usually taken immediately… |
| Insulin (Lantus/Glargine) | ~12 hours; near-flat action over ~24 hours | Individualized and medically supervised — a single daily background dose titrated to fasting glucose. Pharmacology: no pronounced… |
| Insulin (Rapid: Humalog/Novolog) | Serum ~1 hour (subcutaneous); glucose-lowering action lasts 3-5 hours | Individualized and medically supervised — matched to carbohydrate intake and blood glucose (e.g. units per gram of carbohydrate)… |
| Insulin (Regular/Humulin R) | Serum ~1.5 hours (subcutaneous); glucose-lowering action lasts 6-8 hours | Individualized and medically supervised — matched to carbohydrate intake and blood glucose. Pharmacology: onset ~30 minutes, peak… |
| Insulin (Tresiba/Degludec) | ~25 hours; flat action lasting more than 42 hours | Individualized and medically supervised — a single daily background dose. Pharmacology: essentially peakless, duration over 42 ho… |
| Ipa/CJC | Ipamorelin: 2 hours. CJC-1295 (without DAC): 30 minutes. Combined effects provide frequent but shorter duration pulses of growth hormone. | Typical blend: 12mg Ipamorelin + 6mg CJC-1295 (without DAC) per vial. Standard dosing: 100-300mcg Ipamorelin + 100-300mcg CJC-129… |
| Ipamorelin | Approximately 2 hours | Beginner: 100mcg once daily in the morning on empty stomach. Intermediate: 100-200mcg twice daily. Advanced: 200-300mcg 3 times d… |
| Masteron Enanthate | Approximately 8 days | 200-400mg weekly, split into 1-2 injections. Typical range: 200-600mg weekly. (injectable) |
| Masteron Propionate | Approximately 2-3 days | 100-150mg every other day or 150-200mg every 2-3 days. Typical weekly: 300-600mg. (injectable) |
| MK-677 (Ibutamoren) | Approximately 24 hours | Beginner: 10-15mg/day. Standard: 20-25mg/day (most studied dose). Taken orally once daily, typically before bed. (oral) |
| MK-777 (Acetamoren) | Approximately 8-10 hours | 10-30mg per day, taken orally once daily, typically before bed (oral) |
| Primo | Enanthate approx 10.5 days; oral acetate approx 5 hours | Enanthate: 300-600mg weekly. Beginner: 300-400mg/wk. Advanced: 500-600mg/wk. Long ester, dose split 1-2x weekly. (injectable) |
| Proviron | Approximately 12 hours | 25-100mg daily. Common: 25-50mg daily as an ancillary. Higher (75-100mg) for a stronger hardening/libido effect. (oral) |
| Sermorelin | Approximately 10-15 minutes | 200mcg injected subcutaneously before bed on empty stomach. Typical range: 100-300mcg. (injectable) |
| Superdrol | Approximately 8 hours | 10-40mg daily. Beginner: 10-20mg daily. Intermediate: 20-30mg daily. Advanced: 30-40mg daily. Typically run 3-5 weeks. (oral) |
| TB-500 | Approximately 2-3 hours | Loading phase: 5-10mg/week split into 2-3 injections. Maintenance: 2-5mg/week split into 1-2 injections (injectable) |
| Tesamorelin | Approximately 30 minutes | 1-2mg injected subcutaneously before bed on empty stomach (injectable) |
| Thymosin Alpha-1 | Approximately 2 hours | 1.6-3.2mg twice per week subcutaneously or intramuscularly (injectable) |
| Tren Acetate | Approximately 2-3 days | 50-100mg every other day or 75-150mg daily. Typical range: 300-525mg weekly. (injectable) |
| Tren Enanthate | Approximately 10 days | 200-400mg weekly, split into 2 injections. Typical range: 200-600mg weekly. (injectable) |
| Tren Hex | Approximately 14 days | 200-400mg weekly, split into 1-2 injections. Typical range: 200-600mg weekly. (injectable) |
| Turinabol | Approximately 16 hours | 20-80mg daily. Beginner: 20-30mg daily. Intermediate: 40-60mg daily. Advanced: 60-80mg daily. Often run 6-8 weeks. (oral) |
| Winstrol | Oral approx 9 hours; injectable aqueous suspension approx 24 hours | 20-100mg daily, typically split into 2 doses. Beginner: 20-40mg daily. Intermediate: 50-80mg daily. Advanced: 80-100mg daily. (or… |
| Wolverine | BPC-157: 4-6 hours. TB-500: 2-3 hours. Combined effects provide sustained healing throughout the day. | Standard: 500mcg each BPC-157 and TB-500 daily subcutaneously. Aggressive protocols: 1-2mg BPC-157 and 2mg TB-500 daily for 3+ mo… |
| Compound | Half-life | Typical reported dose |
|---|---|---|
| 5-Amino-1MQ | Approximately 4-6 hours | 25-150mg taken orally daily with food (oral) |
| AOD-9604 | Approximately 30 minutes | 200-300mcg injected subcutaneously daily, preferably in the morning (injectable) |
| BAM-15 | Approximately 4-6 hours | 15-30mg taken orally daily with food (oral) |
| Cagrilintide | Extended half-life via fatty acid acylation | Weeks 1-4: 0.25mg (10 units) once weekly. Weeks 5-8: 0.5mg (20 units) weekly. Weeks 9-12: 1.0mg (40 units) weekly. Weeks 13-16: 1… |
| Frag 176-191 | Approximately 30 minutes | 200-500mcg injected subcutaneously in problem areas daily (injectable) |
| MOTS-C | Approximately 3-4 hours | 5-15mg per week total, split into 2 subcutaneous injections (2x/week), or dosed as 5mg every 5 days (injectable) |
| SLU-PP-332 | Approximately 4-6 hours | 100-500mcg taken orally daily, typically 1-2 hours before training (oral) |
| Tesofensine | Approximately 2-3 days | Starting dose: 250mcg daily for weight loss. Most studied dose: 500mcg daily (yielding up to 10% body weight loss over 6 months).… |
| Compound | Half-life | Typical reported dose |
|---|---|---|
| AHK-Cu | Approximately 2-3 hours | 1-5mg injected subcutaneously daily for skin effects (injectable) |
| Cortagen | Varies | 5-30mg injected intramuscularly or subcutaneously daily for 10 days, then maintenance dosing (injectable) |
| Epitalon | Short half-life | 5-10mg injected subcutaneously daily for 10-20 consecutive days, typically before bed. Roughly 100mg per cycle (e.g. 5mg x 20 day… |
| GHK-Cu | Approximately 2-3 hours | 0.5-2mg daily subcutaneously for regenerative effects. Starting dose: 1mg/day to assess tolerance. Moderate: 2mg/day for general… |
| GLOW | GHK-Cu: 2-3 hours. BPC-157: 4-6 hours. TB-500: 2-3 hours. Combined effects provide sustained benefits throughout the day. | Standard: 2mg GHK-Cu + 500mcg BPC-157 + 500mcg TB-500 daily subcutaneously. Typical blend: 50mg GHK-Cu + 10mg BPC-157 + 10mg TB-5… |
| Glutathione | Approximately 2-5 hours | 200-600mg IM, 2-3x per week. IV: 600-2000mg 1-3x per week. (injectable) |
| Humanin | Approximately 2-3 hours | 1-10mg injected subcutaneously 2-3 times per week (injectable) |
| KLOW | BPC-157: 4-6 hours. TB-500: 2-3 hours. GHK-Cu: 2-3 hours. KPV: 2-3 hours. Combined effects provide sustained benefits. | Standard: 500mcg BPC-157 + 500mcg TB-500 + 2mg GHK-Cu + 100-500mcg KPV daily subcutaneously. Typical blend: 10mg BPC-157 + 10mg T… |
| Metformin | Approximately 6.5 hours | 500-2000mg daily, typically split into 2-3 doses. Start with 500mg daily and titrate gradually. (oral) |
| NAD+ | Short half-life, requires frequent administration | Starting: 25mg daily for 1-2 weeks to assess tolerance. Common maintenance: 50mg daily. Higher doses: 100-150mg daily. Some proto… |
| Pinealon | Short half-life | 5-30mg injected subcutaneously daily, typically in the evening before bed (injectable) |
| SS-31 (Elamipretide) | Approximately 2-3 hours | 1-10mg injected subcutaneously daily or every other day (injectable) |
| Thymalin | Varies | 5-30mg injected intramuscularly daily for 10 days, then maintenance dosing 2-3x per week (injectable) |
| Vilon | Varies | 5-30mg injected intramuscularly or subcutaneously daily for 10 days, then maintenance 2-3x per week (injectable) |
| Compound | Half-life | Typical reported dose |
|---|---|---|
| 9-Me-BC | Approximately 4-6 hours | 5-30mg taken orally daily, typically in the morning (oral) |
| Allopregnanolone | Approximately 1-2 hours | 0.1-5mg applied to skin daily (topical) |
| Androsterone | Varies by route - longer with oral/topical | 1-20mg applied to skin daily (topical) |
| Cerebrolysin | Varies | 5-20mg injected intramuscularly or subcutaneously daily. Higher doses (20-30mg) used for acute conditions. Lower maintenance dose… |
| DHEA | Approximately 20-30 minutes | 5-200mg taken daily (oral) |
| Estradiol | Oral: ~12-20 hours; patch: varies; valerate injectable: several days | 0.5-2mg daily; dose varies by indication and formulation (oral) |
| Estradiol Patch | Continuous delivery while patch is worn; system-dependent | 0.025-0.1mg/day patches; apply 1-2x per week depending on product. Replace on schedule (e.g. twice weekly or once weekly). (topic… |
| Estradiol Valerate | Approximately 4-5 days (ester); estradiol release over 1-2 weeks | 2-10mg IM every 1-2 weeks; dose and interval vary by protocol and bloodwork. Common: 4-6mg every 5-7 days or 10mg every 2 weeks.… |
| Noopept | Approximately 1 hour | 10-30mg taken orally 1-3 times daily. Start with 10mg twice daily to assess tolerance. (oral) |
| Progesterone | Approximately 15-20 minutes (very short) | 25-400mg taken daily, typically at night (oral) |
| Selank | Approximately 30 minutes | Starting: 250mcg once daily in the morning. Typical range: 200-1200mcg subcutaneously daily (injectable) |
| Semax | Approximately 20 minutes when injected, longer when used nasally | Starting: 250mcg once daily in the morning. Typical range: 200-1200mcg subcutaneously daily (injectable) |
| Tibolone | Approximately 4-6 hours; metabolites have longer activity | 2.5mg once daily. Lower dose (1.25mg) may be used in some protocols. Take at same time each day. (oral) |
| Compound | Half-life | Typical reported dose |
|---|---|---|
| Amlodipine (Norvasc) | 30-50 hours (very long) | 2.5-10mg once daily. Starting dose typically 5mg. Can be taken with or without food, at same time each day. (oral) |
| Amlodipine/Benazepril | 30-50 hours (amlodipine), 10-11 hours (benazepril) | 2.5/10mg to 10/40mg once daily. Various strength combinations available. Can be taken with or without food. (oral) |
| Atenolol (Tenormin) | 6-7 hours | 25-100mg once daily. Starting dose typically 25-50mg. Can be taken with or without food. (oral) |
| Atorvastatin (Lipitor) | Approximately 14 hours | 10-80mg once daily. Starting dose typically 10-20mg. Can be taken with or without food. (oral) |
| Benazepril (Lotensin) | 10-11 hours | 5-40mg once or twice daily. Starting dose typically 10mg. Can be taken with or without food. (oral) |
| Bisoprolol (Zebeta) | 9-12 hours | 2.5-20mg once daily. Heart failure: start 1.25-2.5mg, titrate slowly. Can be taken with or without food. (oral) |
| Candesartan (Atacand) | 9 hours | 4-32mg once daily. Starting dose typically 8-16mg. Can be taken with or without food. (oral) |
| Carvedilol (Coreg) | 7-10 hours | 3.125-25mg twice daily. Start low and increase gradually. Take with food to reduce dizziness. (oral) |
| Chlorthalidone | 40-60 hours (very long) | 12.5-50mg once daily. Starting dose typically 12.5-25mg. Take in morning. (oral) |
| Diltiazem (Cardizem) | 3-4.5 hours (immediate release), 5-10+ hours (extended release) | 120-360mg daily. Immediate release: 3-4 times daily. Extended release: once or twice daily. Dose varies by formulation. (oral) |
| Enalapril (Vasotec) | 11 hours (active metabolite) | 2.5-40mg daily, given once or twice daily. Starting dose typically 5mg. Can be taken with or without food. (oral) |
| Eplerenone (Inspra) | 4-6 hours | 25-50mg once or twice daily. Post-MI: start 25mg daily. Heart failure: 25-50mg daily. (oral) |
| Ezetimibe (Zetia) | Approximately 22 hours | 10mg once daily. Can be taken with or without food, at any time of day. Often combined with statin. (oral) |
| Fenofibrate (Tricor) | 20 hours | 48-145mg once daily. Dose depends on formulation. Take with food for better absorption (some formulations). (oral) |
| Fluvastatin (Lescol) | 1-3 hours | 20-80mg daily. Immediate release: once or twice daily. Extended release: once daily in evening. (oral) |
| Furosemide (Lasix) | 1.5-2 hours | 20-80mg daily or twice daily. Doses can be much higher in severe cases. Take in morning or early afternoon. (oral) |
| Gemfibrozil (Lopid) | 1.5 hours | 600mg twice daily, 30 minutes before morning and evening meals. (oral) |
| Hydrochlorothiazide (HCTZ) | 6-15 hours | 12.5-50mg once daily. Starting dose typically 12.5-25mg. Take in morning to avoid nighttime urination. (oral) |
| Irbesartan (Avapro) | 11-15 hours | 75-300mg once daily. Starting dose typically 150mg. Can be taken with or without food. (oral) |
| Lisinopril (Zestril/Prinivil) | Approximately 12 hours | 2.5-40mg once daily. Starting dose typically 5-10mg. Take at same time each day, with or without food. (oral) |
| Lisinopril/HCTZ | 12 hours (lisinopril), 6-15 hours (HCTZ) | 10/12.5mg to 20/25mg once daily. Various combinations available. Take in morning. (oral) |
| Losartan (Cozaar) | Approximately 2 hours (active metabolite 6-9 hours) | 25-100mg once daily or divided into 2 doses. Starting dose typically 50mg. Can be taken with or without food. (oral) |
| Lovastatin (Mevacor) | 1-2 hours | 10-80mg daily with evening meal. Starting dose 20mg. Must be taken with food for absorption. (oral) |
| Metoprolol (Lopressor/Toprol XL) | 3-7 hours (immediate release), 15+ hours (extended release) | 25-200mg daily. Immediate release: 2-4 times daily. Extended release (Toprol XL): once daily. Take with or after meals. (oral) |
| Nebivolol (Bystolic) | 12-19 hours (varies by metabolizer status) | 2.5-40mg once daily. Starting dose typically 5mg. Can be taken with or without food. (oral) |
| Niacin (Extended Release) | 20-45 minutes | 500-2000mg once daily at bedtime. Start low and titrate slowly. Take with food or aspirin to reduce flushing. (oral) |
| Nifedipine (Procardia/Adalat) | 2 hours (immediate release), 7 hours (extended release) | 30-90mg once daily (extended release). Immediate release no longer used for hypertension due to rapid effects. (oral) |
| Olmesartan (Benicar) | 13 hours | 5-40mg once daily. Starting dose typically 20mg. Can be taken with or without food. (oral) |
| Perindopril (Aceon) | 3-10 hours (active metabolite) | 2-16mg once daily. Starting dose typically 4mg. Take before meals for best absorption. (oral) |
| Pitavastatin (Livalo) | 12 hours | 1-4mg once daily. Starting dose typically 2mg. Can be taken any time, with or without food. (oral) |
| Pravastatin (Pravachol) | 1.5-2 hours | 10-80mg once daily. Starting dose typically 40mg. Can be taken any time of day, with or without food. (oral) |
| Propranolol (Inderal) | 3-6 hours (immediate), 8-10 hours (extended release) | 40-320mg daily divided. Immediate release: 2-4 times daily. Extended release: once daily. Performance anxiety: 10-40mg as needed.… |
| Quinapril (Accupril) | 2-3 hours | 5-80mg daily, once or divided. Starting dose typically 10-20mg. Can be taken with or without food. (oral) |
| Ramipril (Altace) | 13-17 hours | 1.25-20mg daily, once or divided. Starting dose typically 2.5-5mg. Can be taken with or without food. (oral) |
| Rosuvastatin (Crestor) | Approximately 19 hours | 5-40mg once daily. Starting dose typically 5-10mg. Take at the same time each day, with or without food. (oral) |
| Simvastatin (Zocor) | Approximately 2-3 hours (active metabolites longer) | 5-80mg once daily in the evening. Starting dose typically 10-20mg. Take in evening for best effect. (oral) |
| Spironolactone (Aldactone) | 1.4 hours (active metabolites 16-22 hours) | 12.5-100mg once or twice daily. Heart failure: typically 12.5-25mg daily. Hypertension: 25-100mg daily. (oral) |
| Telmisartan (Micardis) | 24 hours (longest among ARBs) | 20-80mg once daily. Starting dose typically 40mg. Can be taken with or without food. (oral) |
| Valsartan (Diovan) | Approximately 6 hours | 40-320mg once daily. Starting dose typically 80-160mg. Can be taken with or without food. (oral) |
| Verapamil (Calan/Verelan) | 3-7 hours (immediate), 12 hours (extended release) | 120-480mg daily. Immediate release: 3-4 times daily. Extended release: once or twice daily. Varies by indication. (oral) |
| Compound | Half-life | Typical reported dose |
|---|---|---|
| Argireline | Not applicable for topical use | 5-20mg applied topically to facial areas daily (topical) |
| DSIP | Approximately 15 minutes | Starting dose: 75-150mcg, typical range: 100-300mcg subcutaneously before bed, 30-60 minutes before sleep (injectable) |
| KPV | Approximately 2-3 hours | 100-500mcg injected subcutaneously daily (injectable) |
| Melanotan | Approximately 36 hours | 50-100mcg subcutaneously daily for loading phase, then 250-500mcg weekly for maintenance (injectable) |
| Oxytocin | Approximately 1-6 minutes (very short) | 10-40IU injected subcutaneously or intramuscularly as needed (injectable) |
| PT-141 | Approximately 15-20 minutes | Starting dose: 1.25mg, commonly reported dose: 2-3mg injected subcutaneously 30-60 minutes before sexual activity (injectable) |
| Tadalafil | Approximately 17.5 hours | 2.5-20mg daily or as needed. Daily dosing: 2.5-5mg. As needed: 10-20mg 30 minutes before activity. (oral) |
| Compound | Half-life | Typical reported dose |
|---|---|---|
| 5-HTP | Approximately 2-3 hours | 50-500mg daily. Common doses: 100-200mg before bed. Start with lower doses. (oral) |
| Acetyl-L-Carnitine | Approximately 2-3 hours | 250-1500mg daily. Common doses: 500-1000mg daily. Best taken in the morning. (oral) |
| Activated Charcoal | Not applicable | 250-1500mg as needed. Common doses: 500-1000mg. Take away from medications and meals (2 hours before/after). (oral) |
| Allicin | Approximately 2-3 hours | 180-900mg daily. Common doses: 360-540mg daily. Best taken with meals. (oral) |
| Alpha-Lipoic Acid | Approximately 30 minutes | 100-600mg daily. Common doses: 200-400mg daily. Best taken on empty stomach. (oral) |
| Ashwagandha | Not applicable | 300-1200mg daily. Common doses: 450-600mg daily. Look for standardized extracts (withanolides). Best taken with meals. (oral) |
| B-Complex | Varies by B vitamin | 25-100mg daily. Common doses: 50mg daily. Best taken in the morning with food. (oral) |
| Beta-Alanine | Not applicable | 2-6g daily, typically split into 2-3 doses. Common: 3-5g daily. Take with meals to reduce tingling. (oral) |
| Betaine (TMG) | Not applicable | 1-5g daily. Common doses: 2-3g daily. Can be taken with meals or pre-workout. (oral) |
| Boron | Not applicable - mineral | 3-15mg daily. Common dose: 6-9mg daily. Can cycle 2 weeks on, 1 week off. (oral) |
| Citrulline Malate | Approximately 1 hour | 3-10g pre-workout. Common dose: 6-8g 30-60 minutes before training. Can be taken daily. (oral) |
| Citrus Bergamot | Not applicable | 250-1500mg daily. Common doses: 500-1000mg daily. Best taken with meals. (oral) |
| Colostrum | Not applicable | 1-10g daily. Common doses: 2-5g daily. Best taken on empty stomach or with meals. (oral) |
| CoQ10 (Ubiquinone) | Approximately 33 hours | 50-400mg daily. Common doses: 100-200mg daily. Higher doses (300-400mg) for cardiovascular support. (oral) |
| Creatine Monohydrate | Not applicable | Loading: 20-25g daily for 5-7 days, then 3-5g daily maintenance. Or skip loading: 3-5g daily consistently. Can go up to 10g daily… |
| Curcumin | Approximately 6-7 hours | 250-1500mg daily. Common doses: 500-1000mg daily. Best taken with black pepper (piperine) or in liposomal form for better absorpt… |
| D-Aspartic Acid (DAA) | Not applicable | 2-6g daily. Common dose: 3g daily. Some protocols use 2 weeks on, 1 week off. (oral) |
| Fadogia Agrestis | Not applicable | 100-600mg daily. Common doses: 200-400mg daily. Research is limited. (oral) |
| Fenugreek | Not applicable | 250-1200mg daily. Common doses: 500-600mg daily. Look for standardized extracts. (oral) |
| Folate (Folic Acid) | Approximately 100 days | 400-5000mcg daily. Common doses: 400-1000mcg daily. Folate (5-MTHF) form may be better than folic acid. (oral) |
| GABA | Not applicable | 100-1000mg daily. Common doses: 250-500mg before bed. Can be taken as needed or daily. (oral) |
| Glycine | Not applicable | 1-5g before bed. Common dose: 3g 30-60 minutes before sleep. Can be taken with magnesium. (oral) |
| Green Power Blend | Not applicable | 5-20g daily. Common doses: 10-15g daily. Mix with water or smoothies. Best taken in the morning. (oral) |
| HMB (Beta-Hydroxy Beta-Methylbutyrate) | Not applicable | 1-5g daily. Common dose: 3g daily, split into 2-3 doses. Best taken around workouts. (oral) |
| Horny Goat Weed (Icariin) | Not applicable | 250-1000mg daily. Common doses: 500-750mg daily. Look for standardized extracts (icariin content). (oral) |
| Iodine | Not applicable - mineral | 150-1000mcg daily. Common doses: 150-300mcg daily. RDA is 150mcg. Higher doses may be needed for some. (oral) |
| L-Arginine | Approximately 1-2 hours | 2-10g daily. Common doses: 3-6g daily. Often taken pre-workout. Higher doses (8-10g) for specific benefits. (oral) |
| L-Carnitine | Approximately 2-3 hours | 0.5-3g daily. Common doses: 1-2g daily. Can be taken pre-workout or with meals. (oral) |
| L-Theanine | Approximately 2-3 hours | 100-500mg daily. Common doses: 200-400mg daily. Can be taken in morning or before bed. (oral) |
| Maca Root | Not applicable | 1-6g daily. Common doses: 2-3g daily. Best taken with meals. Look for gelatinized maca for better digestion. (oral) |
| Magnesium | Not applicable - mineral | 200-600mg daily. Common doses: 300-400mg daily. Higher doses (600-800mg) may cause loose stools. (oral) |
| Magnesium Glycinate | Not applicable - mineral | 200-600mg daily (elemental magnesium). Common doses: 300-400mg before bed. (oral) |
| Magnesium L-Threonate | Not applicable - mineral | 144-600mg daily (elemental magnesium). Common doses: 200-400mg daily. Best taken before bed. (oral) |
| Melatonin | Approximately 30-60 minutes | 0.5-10mg daily. Common doses: 1-3mg before bed. Start with lower doses (0.5-1mg). (oral) |
| Nattokinase | Approximately 3-4 hours | 1000-6000 FU (Fibrinolytic Units) or 1000-6000mg daily. Common doses: 2000-4000 FU daily. Best taken on empty stomach. (oral) |
| Nicotinamide Riboside (NR) | Approximately 1-2 hours | 125-1000mg daily. Common doses: 250-500mg daily. (oral) |
| NMN (Nicotinamide Mononucleotide) | Approximately 1-2 hours | 125-1000mg daily. Common doses: 250-500mg daily. Higher doses (750-1000mg) for intensive protocols. (oral) |
| Omega-3 (Fish Oil) | Not applicable | 1-5g daily. Common doses: 2-3g daily. Look for high EPA/DHA content (at least 1g combined). (oral) |
| Panax Ginseng | Not applicable | 200-1000mg daily. Common doses: 400-600mg daily. Look for standardized extracts (ginsenosides). (oral) |
| Quercetin | Approximately 3-4 hours | 250-1500mg daily. Common doses: 500-1000mg daily. Often taken with resveratrol. (oral) |
| Resveratrol | Approximately 2-4 hours | 100-1000mg daily. Common doses: 250-500mg daily. Best taken with fat for absorption. (oral) |
| Saw Palmetto | Not applicable | 160-960mg daily. Common doses: 320-640mg daily. Look for standardized extracts. (oral) |
| Selenium | Not applicable - mineral | 50-400mcg daily. Common doses: 100-200mcg daily. Don't exceed 400mcg daily. (oral) |
| Shilajit | Not applicable | 250-1000mg daily. Common dose: 500mg daily. Best taken with meals. (oral) |
| Stinging Nettle Root | Not applicable | 300-1200mg daily. Common doses: 600-900mg daily. Best taken with meals. (oral) |
| Taurine | Not applicable | 1-5g daily. Common doses: 2-3g daily. Can be taken with meals or pre-workout. (oral) |
| Thiamine (Vitamin B1) | Approximately 9-18 days | 10-200mg daily. Common doses: 25-100mg daily. Best taken with meals. (oral) |
| Tongkat Ali (Eurycoma Longifolia) | Not applicable | 100-600mg daily. Common doses: 200-400mg daily. Look for standardized extracts (1% eurypeptides). (oral) |
| Tribulus Terrestris | Not applicable | 250-1500mg daily. Common doses: 500-1000mg daily. Look for standardized extracts (40% saponins). (oral) |
| Ubiquinol | Approximately 33 hours | 50-300mg daily. Common dose: 100-200mg daily. More bioavailable than ubiquinone. (oral) |
| Vitamin B12 | Approximately 6 days | 100-5000mcg daily. Common doses: 500-1000mcg daily. Sublingual or methylcobalamin forms may be better absorbed. (oral) |
| Vitamin B6 | Approximately 15-20 days | 10-100mg daily. Common doses: 25-50mg daily. Best taken with meals. (oral) |
| Vitamin C | Approximately 30 minutes | 500mg-5g daily. Common doses: 1-2g daily. Higher doses (3-5g) for immune support or during illness. (oral) |
| Vitamin D3 | Approximately 2-3 weeks | 1000-5000 IU daily. Many TRT users take 2000-4000 IU daily. Higher doses (5000-10000 IU) may be needed for deficiency correction.… |
| Vitamin E | Approximately 2-3 days | 100-800 IU daily. Common doses: 200-400 IU daily. Best taken with meals containing fat. (oral) |
| Vitamin K2 (MK-4) | Approximately 1-2 hours | 50-300mcg daily. Common dose: 100-200mcg daily. Often taken with Vitamin D3. (oral) |
| Vitamin K2 (MK-7) | Approximately 3 days (much longer than MK-4) | 50-300mcg daily. Common dose: 100-200mcg daily. Longer-acting than MK-4. (oral) |
| Zinc | Not applicable - mineral | 10-30mg daily. TRT users often take 15-25mg daily. Higher doses (30-50mg) may be used short-term but can cause copper deficiency.… |