Half-life, typical dosing and reconstitution for the 217 compounds tracked in OptiPin – TRT esters, GLP-1 agonists (semaglutide, tirzepatide, retatrutide), growth & recovery peptides, fat-loss and longevity compounds, and more. Educational only; consult a licensed provider before use.
This is a reference table. Some of what it lists can hurt you quickly. Shakiness, sweating, confusion or a pounding heart on any insulin or GLP-1 is possible hypoglycemia: take 15 g of fast carbohydrate and get help if it does not settle. An injection site that turns red, hot or hard, redness that spreads, or a fever after injecting, needs same-day medical care. Chest pain, breathlessness, or pain and swelling in one calf needs emergency care. Swelling of the lips, tongue or throat, or trouble breathing, is an emergency. Nothing here is for use in pregnancy without a prescriber saying so, and that goes double for anything hormonal.
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Every compound in the OptiPin library, with its half-life and a typical reported dose. Educational reference only — dosing is set by a licensed prescriber, not by this table. Use the search and filters above to open the full card for any entry.
| Compound | Half-life | Typical reported dose |
|---|---|---|
| Clomiphene Citrate | Approximately 5-7 days | 25-50mg daily or every other day. Typical PCT protocol: 50mg daily for 4-6 weeks. (oral) |
| DHT | Approximately 50-60 minutes | 100-250mg daily applied to skin, which is the route the approved gel uses (topical) |
| DHT Enanthate | Approximately 5-7 days | 5-40mg weekly, split into 1-2 injections IM. Typical dose: 10-20mg weekly. Start low and increase gradually. (injectable) |
| DHT Propionate | Approximately 1-2 days | 1-20mg every other day or 2-3x per week IM. Typical dose: 5-10mg every other day. Start low and increase gradually. (injectable) |
| DIM (Diindolylmethane) | Approximately 3-4 hours | 100-300mg daily with food. Start at 100mg and increase as needed. (oral) |
| Enclomiphene | Approximately 24 hours | 12.5-25mg daily. Typical dose 12.5mg daily or every other day. Titrate based on response and bloodwork. (oral) |
| Estrogen Blocker (Anastrozole) | Approximately 50 hours | 0.25-1.0mg every other day or 2-3x per week. Start low and adjust based on bloodwork. (oral) |
| Exemestane | Approximately 24 hours | TRT support: 6.25-25mg daily or every other day. Start low (6.25mg) and titrate based on bloodwork. (oral) |
| Gonadorelin | Approximately 10-15 minutes | Community-reported: 100-250mcg subcutaneously or intramuscularly, 2-3x per week. This does not follow from a 10-minute half-life… |
| hCG (Human Chorionic Gonadotropin) | Approximately 24-36 hours | Fertility (female only): 5,000-10,000 IU as single dose to trigger ovulation. Male fertility/TRT: 250-500 IU 2-3x per week. (inje… |
| Testosterone Cypionate | Approximately 3.8 days (population PK model; product label states ~8 days) | TRT: 50-200mg every 2-7 days IM or SubQ. Typical dose: 100-200mg weekly. (injectable) |
| Testosterone Decanoate | Approximately 5.6 days | TRT: 50-200mg every 3.5-14 days IM. Typical dose: 100mg every 3.5 days (twice weekly) or 200-400mg every 2-4 weeks. (injectable) |
| Testosterone Enanthate | Approximately 4.5 days | TRT: 50-200mg every 5-7 days IM or 2-3.5 days subcutaneously. Typical dose: 100-200mg weekly. (injectable) |
| Testosterone Gel | Varies, but provides daily dosing for stability | 25-100mg daily applied to clean, dry skin on shoulders, upper arms, or abdomen (topical) |
| Testosterone Isocaproate | Approximately 7 days | TRT: 50-150mg every 3-7 days IM or subcutaneously. Typical dose: 100-200mg every week. (injectable) |
| Testosterone Patch | Continuous delivery over 24 hours | 2-10mg patch applied to the back, abdomen, thigh, or upper arm daily (topical) |
| Testosterone Phenylpropionate | Approximately 2.5 days | Rarely used alone; in blends typically 50-100mg per injection. Standalone TRT: 50-100mg every 3-5 days IM. (injectable) |
| Testosterone Propionate | Approximately 19-20 hours | TRT: 50-100mg every 2-3 days IM or 1-2.5 days subcutaneously. Typical dose: 50mg every other day. (injectable) |
| Testosterone Sustanon | Blend; approximately 2-3 weeks effective duration | TRT: 250mg every 2-3 weeks IM, or 125mg every 1-2 weeks. Some protocols use 250mg weekly or split doses. (injectable) |
| Testosterone Undecanoate | Approximately 20-34 days (injectable) | 1000mg IM every 10-14 weeks (follow product labeling). Loading may involve two injections 4-6 weeks apart. (injectable) |
| Compound | Half-life | Typical reported dose |
|---|---|---|
| Albiglutide | Approximately 5 days | 30-50mg injected once weekly subcutaneously (injectable) |
| Amycretin | Engineered for weekly subcutaneous dosing. A precise published human half-life is not established. | Trial protocols escalate stepwise over months. No consumer dosing schedule exists and published ranges are specific to the trial… |
| Dulaglutide | Approximately 5 days | Start at 0.75mg weekly, can increase to 4.5mg weekly. Weekly subcutaneous injections. (injectable) |
| Exenatide | Approximately 2.4 hours | 5-10mcg injected twice daily, before morning and evening meals (injectable) |
| Exenatide Extended Release | Approximately 5 days (extended release) | 2mg injected once weekly subcutaneously (injectable) |
| Liraglutide | Approximately 13 hours | For weight loss: Start at 0.6mg daily, titrate to 3.0mg over 4-8 weeks. Daily injections subcutaneously. (injectable) |
| Lixisenatide | Approximately 3 hours | 10-20mcg injected once daily within 1 hour before first meal (injectable) |
| Mazdutide | Once-weekly dosing provides sustained effect | Weeks 1-4: 1-2mg/week (20-40 units). Weeks 5-8: 3-4mg/week (60-80 units) if tolerated. Weeks 9+: 4-6mg/week (80-120 units) for ma… |
| Orforglipron | Approximately 29-49 hours (very long) | Type 2 Diabetes: 3mg, 12mg, or 36mg daily. Weight Management: 12mg, 24mg, or 36mg daily (up to 12% body weight reduction over 72… |
| Retatrutide | Approximately 6-8 days (150-200 hours) | Weeks 1-4: 1mg once weekly (starting dose to assess tolerance). Weeks 5-8: 2mg once weekly (gradually increase if tolerated). Wee… |
| Semaglutide | Approximately 1 week | Weeks 1-4: 0.25mg weekly. Weeks 5-8: 0.5mg weekly. Weeks 9-12: 1.0mg weekly. Weeks 13-16: 1.7mg weekly. Week 17+: 2.4mg weekly (m… |
| Survodutide | Approximately 5-7 days | Weeks 1-4: 0.6mg weekly. Weeks 5-8: 1.2mg weekly. Weeks 9-12: 2.4mg weekly. Weeks 13-16: 3.6mg weekly. Weeks 17+: 4.8mg weekly (m… |
| Tirzepatide | Approximately 5 days | Weeks 1-4: 2.5mg weekly. Weeks 5-8: 5mg weekly. Weeks 9-12: 7.5mg weekly. Weeks 13-16: 10mg weekly (if needed). Weeks 17-20: 12.5… |
| Compound | Half-life | Typical reported dose |
|---|---|---|
| Actovegin | Varies | 5-20mg injected intramuscularly or intravenously daily. Higher doses (20-40mg) used for acute conditions. Lower maintenance doses… |
| Anadrol | Approximately 8-9 hours | 25-150mg daily. Beginner: 25-50mg daily. Intermediate: 50-100mg daily. Advanced: 100-150mg daily. Usually run 4-6 weeks. (oral) |
| Anavar | Approximately 9-10 hours | Men: 20-80mg daily, typically split into 2 doses. Women: 5-20mg daily. Beginner: 20-40mg daily. (oral) |
| ARA-290 | Short; daily dosing is standard. | 2–4 mg subcutaneously once daily. Clinical trials have used 4 mg daily for 28 days; 2 mg daily is also common for maintenance or… |
| BPC-157 | 4-6 hours | 100-500mcg 1-2x daily, subcutaneously for 100-1000mcg total daily (injectable) |
| CJC-1295 (with DAC) | Approximately 6-8 days | 500-1000mcg per injection, 1-2 times per week. Total weekly dose: 1000-2000mcg, bodybuilders reportedly use up to 4000mcg weekly… |
| CJC-1295 (without DAC) | Approximately 30 minutes | 100-300mcg per injection, 1-3 times daily injected subcutaneously before bed on empty stomach (injectable) |
| Deca | Approximately 15 days | 200-600mg weekly, typically split into 1-2 injections. Beginner: 200-300mg weekly. Intermediate: 300-400mg weekly. Advanced: 400-… |
| DHB | Depends on ester (propionate approx 2 days; cypionate approx 6-8 days) | 300-500mg weekly (commonly as the propionate or cypionate ester). Beginner: 200-300mg/wk. Advanced: 400-500mg/wk. Dose split freq… |
| Dianabol | Approximately 4.5-6 hours | 10-50mg daily, typically split into 2-3 doses. Beginner: 10-20mg daily. Intermediate: 25-40mg daily. Advanced: 40-50mg daily. (or… |
| EQ | Approximately 14-16 days | 200-600mg per week IM, typically split into 1-2 injections. Common dose 400mg/week. Lower doses (200-300mg) for mild cycles. (inj… |
| GHRP-2 | Approximately 30 minutes | 100-200mcg injected subcutaneously 2-3x daily on empty stomach (injectable) |
| GHRP-6 | Approximately 20-30 minutes | 100-200mcg injected subcutaneously 1-3x daily on empty stomach (injectable) |
| GLP-2 | Approximately 7 minutes (very short) | 1-5mg injected subcutaneously daily (injectable) |
| Halotestin | Approximately 9 hours | 10-40mg daily. Beginner: 10mg daily. Intermediate: 20mg daily. Advanced: 30-40mg daily. Often used only in the final 2-4 weeks be… |
| Hexarelin | Approximately 20-30 minutes | 100-200mcg injected subcutaneously 1-2x daily on empty stomach (injectable) |
| HGH (Somatropin) | Approximately 3-4 hours | 1-4 IU daily injected subcutaneously in the morning or before bed. Typically no more than1-2 IU for longevity purposes. Advanced… |
| IGF-1 LR3 | Approximately 20-30 hours | Beginners: 20-50mcg daily post-workout. Intermediate/Advanced: 50-100mcg daily. Some split doses AM/PM. Usually taken immediately… |
| Insulin (Lantus/Glargine) | ~12 hours; near-flat action over ~24 hours | Individualized and medically supervised — a single daily background dose titrated to fasting glucose. Pharmacology: no pronounced… |
| Insulin (Rapid: Humalog/Novolog) | Serum ~1 hour (subcutaneous); glucose-lowering action lasts 3-5 hours | Individualized and medically supervised — matched to carbohydrate intake and blood glucose (e.g. units per gram of carbohydrate)… |
| Insulin (Regular/Humulin R) | Serum ~1.5 hours (subcutaneous); glucose-lowering action lasts 6-8 hours | Individualized and medically supervised — matched to carbohydrate intake and blood glucose. Pharmacology: onset ~30 minutes, peak… |
| Insulin (Tresiba/Degludec) | ~25 hours; flat action lasting more than 42 hours | Individualized and medically supervised — a single daily background dose. Pharmacology: essentially peakless, duration over 42 ho… |
| Ipa/CJC | Ipamorelin: 2 hours. CJC-1295 (without DAC): 30 minutes. Combined effects provide frequent but shorter duration pulses of growth hormone. | Typical blend: 12mg Ipamorelin + 6mg CJC-1295 (without DAC) per vial. Standard dosing: 100-300mcg Ipamorelin + 100-300mcg CJC-129… |
| Ipamorelin | Approximately 2 hours | Beginner: 100mcg once daily in the morning on empty stomach. Intermediate: 100-200mcg twice daily. Advanced: 200-300mcg 3 times d… |
| Masteron Enanthate | Approximately 7 days | 200-400mg weekly, split into 1-2 injections. Typical range: 200-600mg weekly. (injectable) |
| Masteron Propionate | Approximately 2-3 days | 100-150mg every other day or 150-200mg every 2-3 days. Typical weekly: 300-600mg. (injectable) |
| MK-677 (Ibutamoren) | Approximately 24 hours | Beginner: 10-15mg/day. Standard: 20-25mg/day (most studied dose). Taken orally once daily, typically before bed. (oral) |
| MK-777 (Acetamoren) | Approximately 8-10 hours | 10-30mg per day, taken orally once daily, typically before bed (oral) |
| Primo | Enanthate approx 10.5 days; oral acetate approx 5 hours | Enanthate: 300-600mg weekly. Beginner: 300-400mg/wk. Advanced: 500-600mg/wk. Long ester, dose split 1-2x weekly. (injectable) |
| Proviron | Approximately 12 hours | 25-100mg daily. Common: 25-50mg daily as an ancillary. Higher (75-100mg) for a stronger hardening/libido effect. (oral) |
| Sermorelin | Approximately 10-15 minutes | 200mcg injected subcutaneously before bed on empty stomach. Typical range: 100-300mcg. (injectable) |
| Superdrol | Approximately 8 hours | 10-40mg daily. Beginner: 10-20mg daily. Intermediate: 20-30mg daily. Advanced: 30-40mg daily. Typically run 3-5 weeks. (oral) |
| TB-500 | Approximately 5 hours | Loading phase: 5-10mg/week split into 2-3 injections. Maintenance: 2-5mg/week split into 1-2 injections (injectable) |
| Tesamorelin | Approximately 30 minutes | 1-2mg injected subcutaneously before bed on empty stomach (injectable) |
| Thymosin Alpha-1 | Approximately 2 hours | 1.6-3.2mg twice per week subcutaneously or intramuscularly (injectable) |
| Tren Acetate | Approximately 2-3 days | 50-100mg every other day or 75-150mg daily. Typical range: 300-525mg weekly. (injectable) |
| Tren Enanthate | Approximately 10 days | 200-400mg weekly, split into 2 injections. Typical range: 200-600mg weekly. (injectable) |
| Tren Hex | Approximately 14 days | 200-400mg weekly, split into 1-2 injections. Typical range: 200-600mg weekly. (injectable) |
| Turinabol | Approximately 16 hours | 20-80mg daily. Beginner: 20-30mg daily. Intermediate: 40-60mg daily. Advanced: 60-80mg daily. Often run 6-8 weeks. (oral) |
| Winstrol | Oral approx 9 hours; injectable aqueous suspension approx 24 hours | 20-100mg daily, typically split into 2 doses. Beginner: 20-40mg daily. Intermediate: 50-80mg daily. Advanced: 80-100mg daily. (or… |
| Wolverine | BPC-157: 4-6 hours. TB-500: 2-3 hours. Combined effects provide sustained healing throughout the day. | Standard: 500mcg each BPC-157 and TB-500 daily subcutaneously. Aggressive protocols: 1-2mg BPC-157 and 2mg TB-500 daily for 3+ mo… |
| Compound | Half-life | Typical reported dose |
|---|---|---|
| 5-Amino-1MQ | Approximately 4-6 hours | 25-150mg taken orally daily with food (oral) |
| AOD-9604 | Approximately 30 minutes | 200-300mcg injected subcutaneously daily, preferably in the morning (injectable) |
| BAM-15 | Approximately 4-6 hours | 15-30mg taken orally daily with food (oral) |
| Cagrilintide | Extended half-life via fatty acid acylation | Weeks 1-4: 0.25mg (10 units) once weekly. Weeks 5-8: 0.5mg (20 units) weekly. Weeks 9-12: 1.0mg (40 units) weekly. Weeks 13-16: 1… |
| Eloralintide | Long-acting, engineered for once-weekly dosing. A precise published human half-life is not established. | Trial protocols use weekly subcutaneous dosing with a stepwise escalation. Published dose ranges are trial-specific and no consum… |
| Frag 176-191 | Approximately 30 minutes | 200-500mcg injected subcutaneously in problem areas daily (injectable) |
| MOTS-C | Approximately 3-4 hours | 5-15mg per week total, split into 2 subcutaneous injections (2x/week), or dosed as 5mg every 5 days (injectable) |
| SLU-PP-332 | Approximately 4-6 hours | 100-500mcg taken orally daily, typically 1-2 hours before training (oral) |
| Tesofensine | Approximately 2-3 days | Starting dose: 250mcg daily for weight loss. Most studied dose: 500mcg daily (yielding up to 10% body weight loss over 6 months).… |
| Compound | Half-life | Typical reported dose |
|---|---|---|
| AHK-Cu | Approximately 2-3 hours | 1-5mg injected subcutaneously daily for skin effects (injectable) |
| Cartalax | Short half-life | 5-20mg injected subcutaneously or intramuscularly daily for a short course, commonly 10 days (injectable) |
| Cortagen | Varies | 5-30mg injected intramuscularly or subcutaneously daily for 10 days, then maintenance dosing (injectable) |
| Epitalon | Short half-life | 5-10mg injected subcutaneously daily for 10-20 consecutive days, typically before bed. Roughly 100mg per cycle (e.g. 5mg x 20 day… |
| GHK-Cu | Approximately 2-3 hours | 0.5-2mg daily subcutaneously for regenerative effects. Starting dose: 1mg/day to assess tolerance. Moderate: 2mg/day for general… |
| GLOW | GHK-Cu: 2-3 hours. BPC-157: 4-6 hours. TB-500: 2-3 hours. Combined effects provide sustained benefits throughout the day. | Standard: 2mg GHK-Cu + 500mcg BPC-157 + 500mcg TB-500 daily subcutaneously. Typical blend: 50mg GHK-Cu + 10mg BPC-157 + 10mg TB-5… |
| Glutathione | Approximately 2-5 hours | 200-600mg IM, 2-3x per week. IV: 600-2000mg 1-3x per week. (injectable) |
| Humanin | Approximately 2-3 hours | 1-10mg injected subcutaneously 2-3 times per week (injectable) |
| KLOW | BPC-157: 4-6 hours. TB-500: 2-3 hours. GHK-Cu: 2-3 hours. KPV: 2-3 hours. Combined effects provide sustained benefits. | Standard: 500mcg BPC-157 + 500mcg TB-500 + 2mg GHK-Cu + 100-500mcg KPV daily subcutaneously. Typical blend: 10mg BPC-157 + 10mg T… |
| Metformin | Approximately 6.5 hours | 500-2000mg daily, typically split into 2-3 doses. Start with 500mg daily and titrate gradually. (oral) |
| NAD+ | Short half-life, requires frequent administration | Starting: 25mg daily for 1-2 weeks to assess tolerance. Common maintenance: 50mg daily. Higher doses: 100-150mg daily. Some proto… |
| Pinealon | Short half-life | 5-30mg injected subcutaneously daily, typically in the evening before bed (injectable) |
| SS-31 (Elamipretide) | Approximately 2-3 hours | 1-10mg injected subcutaneously daily or every other day (injectable) |
| Thymalin | Varies | 5-30mg injected intramuscularly daily for 10 days, then maintenance dosing 2-3x per week (injectable) |
| Vilon | Varies | 5-30mg injected intramuscularly or subcutaneously daily for 10 days, then maintenance 2-3x per week (injectable) |
| Compound | Half-life | Typical reported dose |
|---|---|---|
| 9-Me-BC | Approximately 4-6 hours | 5-30mg taken orally daily, typically in the morning (oral) |
| Allopregnanolone | Approximately 1-2 hours | 0.1-5mg applied to skin daily (topical) |
| Androsterone | Varies by route - longer with oral/topical | 1-20mg applied to skin daily (topical) |
| Cerebrolysin | Varies | Dosed by volume, not by weight. The standard solution is 215.2mg/mL, so 1mL is about 215mg. Manufacturer daily ranges are 10-30mL… |
| DHEA | Approximately 20-30 minutes | 5-200mg taken daily (oral) |
| Estradiol | Oral: ~12-20 hours; patch: varies; valerate injectable: several days | 0.5-2mg daily; dose varies by indication and formulation (oral) |
| Estradiol Patch | Continuous delivery while patch is worn; system-dependent | 0.025-0.1mg/day patches; apply 1-2x per week depending on product. Replace on schedule (e.g. twice weekly or once weekly). (topic… |
| Estradiol Valerate | Approximately 4-5 days (ester); estradiol release over 1-2 weeks | 2-10mg IM every 1-2 weeks; dose and interval vary by protocol and bloodwork. Common: 4-6mg every 5-7 days or 10mg every 2 weeks.… |
| Noopept | Approximately 1 hour | 10-30mg taken orally 1-3 times daily. Start with 10mg twice daily to assess tolerance. (oral) |
| Progesterone | Oral micronized approximately 16-18 hours; intravenous, minutes | 25-400mg taken daily, typically at night (oral) |
| Selank | Approximately 30 minutes | Starting: 250mcg once daily in the morning. Typical range: 200-1200mcg subcutaneously daily (injectable) |
| Semax | Approximately 20 minutes when injected, longer when used nasally | Starting: 250mcg once daily in the morning. Typical range: 200-1200mcg subcutaneously daily (injectable) |
| Tibolone | Approximately 4-6 hours; metabolites have longer activity | 2.5mg once daily. Lower dose (1.25mg) may be used in some protocols. Take at same time each day. (oral) |
| Compound | Half-life | Typical reported dose |
|---|---|---|
| Amlodipine (Norvasc) | 30-50 hours (very long) | 2.5-10mg once daily. Starting dose typically 5mg. Can be taken with or without food, at same time each day. (oral) |
| Amlodipine/Benazepril | 30-50 hours (amlodipine), 10-11 hours (benazepril) | 2.5/10mg to 10/40mg once daily. Various strength combinations available. Can be taken with or without food. (oral) |
| Atenolol (Tenormin) | 6-7 hours | 25-100mg once daily. Starting dose typically 25-50mg. Can be taken with or without food. (oral) |
| Atorvastatin (Lipitor) | Approximately 14 hours | 10-80mg once daily. Starting dose typically 10-20mg. Can be taken with or without food. (oral) |
| Benazepril (Lotensin) | 10-11 hours | 5-40mg once or twice daily. Starting dose typically 10mg. Can be taken with or without food. (oral) |
| Bisoprolol (Zebeta) | 9-12 hours | 2.5-20mg once daily. Heart failure: start 1.25-2.5mg, titrate slowly. Can be taken with or without food. (oral) |
| Candesartan (Atacand) | 9 hours | 4-32mg once daily. Starting dose typically 8-16mg. Can be taken with or without food. (oral) |
| Carvedilol (Coreg) | 7-10 hours | 3.125-25mg twice daily. Start low and increase gradually. Take with food to reduce dizziness. (oral) |
| Chlorthalidone | 40-60 hours (very long) | 12.5-50mg once daily. Starting dose typically 12.5-25mg. Take in morning. (oral) |
| Diltiazem (Cardizem) | 3-4.5 hours (immediate release), 5-10+ hours (extended release) | 120-360mg daily. Immediate release: 3-4 times daily. Extended release: once or twice daily. Dose varies by formulation. (oral) |
| Enalapril (Vasotec) | 11 hours (active metabolite) | 2.5-40mg daily, given once or twice daily. Starting dose typically 5mg. Can be taken with or without food. (oral) |
| Eplerenone (Inspra) | 4-6 hours | 25-50mg once or twice daily. Post-MI: start 25mg daily. Heart failure: 25-50mg daily. (oral) |
| Ezetimibe (Zetia) | Approximately 22 hours | 10mg once daily. Can be taken with or without food, at any time of day. Often combined with statin. (oral) |
| Fenofibrate (Tricor) | 20 hours | 48-145mg once daily. Dose depends on formulation. Take with food for better absorption (some formulations). (oral) |
| Fluvastatin (Lescol) | 1-3 hours | 20-80mg daily. Immediate release: once or twice daily. Extended release: once daily in evening. (oral) |
| Furosemide (Lasix) | 1.5-2 hours | 20-80mg daily or twice daily. Doses can be much higher in severe cases. Take in morning or early afternoon. (oral) |
| Gemfibrozil (Lopid) | 1.5 hours | 600mg twice daily, 30 minutes before morning and evening meals. (oral) |
| Hydrochlorothiazide (HCTZ) | 6-15 hours | 12.5-50mg once daily. Starting dose typically 12.5-25mg. Take in morning to avoid nighttime urination. (oral) |
| Irbesartan (Avapro) | 11-15 hours | 75-300mg once daily. Starting dose typically 150mg. Can be taken with or without food. (oral) |
| Lisinopril (Zestril/Prinivil) | Approximately 12 hours | 2.5-40mg once daily. Starting dose typically 5-10mg. Take at same time each day, with or without food. (oral) |
| Lisinopril/HCTZ | 12 hours (lisinopril), 6-15 hours (HCTZ) | 10/12.5mg to 20/25mg once daily. Various combinations available. Take in morning. (oral) |
| Losartan (Cozaar) | Approximately 2 hours (active metabolite 6-9 hours) | 25-100mg once daily or divided into 2 doses. Starting dose typically 50mg. Can be taken with or without food. (oral) |
| Lovastatin (Mevacor) | 1-2 hours | 10-80mg daily with evening meal. Starting dose 20mg. Must be taken with food for absorption. (oral) |
| Metoprolol (Lopressor/Toprol XL) | 3-7 hours (immediate release), 15+ hours (extended release) | 25-200mg daily. Immediate release: 2-4 times daily. Extended release (Toprol XL): once daily. Take with or after meals. (oral) |
| Nebivolol (Bystolic) | 12-19 hours (varies by metabolizer status) | 2.5-40mg once daily. Starting dose typically 5mg. Can be taken with or without food. (oral) |
| Niacin (Extended Release) | 20-45 minutes | 500-2000mg once daily at bedtime. Start low and titrate slowly. Take with food or aspirin to reduce flushing. (oral) |
| Nifedipine (Procardia/Adalat) | 2 hours (immediate release), 7 hours (extended release) | 30-90mg once daily (extended release). Immediate release no longer used for hypertension due to rapid effects. (oral) |
| Olmesartan (Benicar) | 13 hours | 5-40mg once daily. Starting dose typically 20mg. Can be taken with or without food. (oral) |
| Perindopril (Aceon) | 3-10 hours (active metabolite) | 2-16mg once daily. Starting dose typically 4mg. Take before meals for best absorption. (oral) |
| Pitavastatin (Livalo) | 12 hours | 1-4mg once daily. Starting dose typically 2mg. Can be taken any time, with or without food. (oral) |
| Pravastatin (Pravachol) | 1.5-2 hours | 10-80mg once daily. Starting dose typically 40mg. Can be taken any time of day, with or without food. (oral) |
| Propranolol (Inderal) | 3-6 hours (immediate), 8-10 hours (extended release) | 40-320mg daily divided. Immediate release: 2-4 times daily. Extended release: once daily. Performance anxiety: 10-40mg as needed.… |
| Quinapril (Accupril) | 2-3 hours | 5-80mg daily, once or divided. Starting dose typically 10-20mg. Can be taken with or without food. (oral) |
| Ramipril (Altace) | 13-17 hours | 1.25-20mg daily, once or divided. Starting dose typically 2.5-5mg. Can be taken with or without food. (oral) |
| Rosuvastatin (Crestor) | Approximately 19 hours | 5-40mg once daily. Starting dose typically 5-10mg. Take at the same time each day, with or without food. (oral) |
| Simvastatin (Zocor) | Approximately 2-3 hours (active metabolites longer) | 5-80mg once daily in the evening. Starting dose typically 10-20mg. Take in evening for best effect. (oral) |
| Spironolactone (Aldactone) | 1.4 hours (active metabolites 16-22 hours) | 12.5-100mg once or twice daily. Heart failure: typically 12.5-25mg daily. Hypertension: 25-100mg daily. (oral) |
| Telmisartan (Micardis) | 24 hours (longest among ARBs) | 20-80mg once daily. Starting dose typically 40mg. Can be taken with or without food. (oral) |
| Valsartan (Diovan) | Approximately 6 hours | 40-320mg once daily. Starting dose typically 80-160mg. Can be taken with or without food. (oral) |
| Verapamil (Calan/Verelan) | 3-7 hours (immediate), 12 hours (extended release) | 120-480mg daily. Immediate release: 3-4 times daily. Extended release: once or twice daily. Varies by indication. (oral) |
| Compound | Half-life | Typical reported dose |
|---|---|---|
| Argireline | Not applicable for topical use | 5-20mg applied topically to facial areas daily (topical) |
| DSIP | Approximately 15 minutes | Starting dose: 75-150mcg, typical range: 100-300mcg subcutaneously before bed, 30-60 minutes before sleep (injectable) |
| Kisspeptin | Short. Kisspeptin-10 clears within minutes; kisspeptin-54 is longer at roughly half an hour. Both are far shorter than the peptides usually dosed weekly. | Research protocols use intravenous infusion or bolus, dosed per kilogram, under clinical supervision. There is no established sub… |
| KPV | Approximately 2-3 hours | 100-500mcg injected subcutaneously daily (injectable) |
| Melanotan | Approximately 36 hours | 50-100mcg subcutaneously daily for loading phase, then 250-500mcg weekly for maintenance (injectable) |
| Oxytocin | Approximately 1-6 minutes (very short) | 10-40IU injected subcutaneously or intramuscularly as needed (injectable) |
| PT-141 | Approximately 15-20 minutes | Starting dose: 1.25mg, commonly reported dose: 2-3mg injected subcutaneously 30-60 minutes before sexual activity (injectable) |
| Tadalafil | Approximately 17.5 hours | 2.5-20mg daily or as needed. Daily dosing: 2.5-5mg. As needed: 10-20mg 30 minutes before activity. (oral) |
| Compound | Half-life | Typical reported dose |
|---|---|---|
| 5-HTP | Approximately 2-3 hours | 50-500mg daily. Common doses: 100-200mg before bed. Start with lower doses. (oral) |
| Acetyl-L-Carnitine | Approximately 2-3 hours | 250-1500mg daily. Common doses: 500-1000mg daily. Best taken in the morning. (oral) |
| Activated Charcoal | Not applicable | 250-1500mg as needed. Common doses: 500-1000mg. Take away from medications and meals (2 hours before/after). (oral) |
| Allicin | Approximately 2-3 hours | 180-900mg daily. Common doses: 360-540mg daily. Best taken with meals. (oral) |
| Alpha-Lipoic Acid | Approximately 30 minutes | 100-600mg daily. Common doses: 200-400mg daily. Best taken on empty stomach. (oral) |
| Ashwagandha | Not applicable | 300-1200mg daily. Common doses: 450-600mg daily. Look for standardized extracts (withanolides). Best taken with meals. (oral) |
| B-Complex | Varies by B vitamin | 25-100mg daily. Common doses: 50mg daily. Best taken in the morning with food. (oral) |
| Beta-Alanine | Not applicable | 2-6g daily, typically split into 2-3 doses. Common: 3-5g daily. Take with meals to reduce tingling. (oral) |
| Betaine (TMG) | Not applicable | 1-5g daily. Common doses: 2-3g daily. Can be taken with meals or pre-workout. (oral) |
| Boron | Not applicable - mineral | 3-15mg daily. Common dose: 6-9mg daily. Can cycle 2 weeks on, 1 week off. (oral) |
| Citrulline Malate | Approximately 1 hour | 3-10g pre-workout. Common dose: 6-8g 30-60 minutes before training. Can be taken daily. (oral) |
| Citrus Bergamot | Not applicable | 250-1500mg daily. Common doses: 500-1000mg daily. Best taken with meals. (oral) |
| Colostrum | Not applicable | 1-10g daily. Common doses: 2-5g daily. Best taken on empty stomach or with meals. (oral) |
| CoQ10 (Ubiquinone) | Approximately 33 hours | 50-400mg daily. Common doses: 100-200mg daily. Higher doses (300-400mg) for cardiovascular support. (oral) |
| Creatine Monohydrate | Not applicable | Loading: 20-25g daily for 5-7 days, then 3-5g daily maintenance. Or skip loading: 3-5g daily consistently. Can go up to 10g daily… |
| Curcumin | Approximately 6-7 hours | 250-1500mg daily. Common doses: 500-1000mg daily. Best taken with black pepper (piperine) or in liposomal form for better absorpt… |
| D-Aspartic Acid (DAA) | Not applicable | 2-6g daily. Common dose: 3g daily. Some protocols use 2 weeks on, 1 week off. (oral) |
| Fadogia Agrestis | Not applicable | 100-600mg daily. Common doses: 200-400mg daily. Research is limited. (oral) |
| Fenugreek | Not applicable | 250-1200mg daily. Common doses: 500-600mg daily. Look for standardized extracts. (oral) |
| Folate (Folic Acid) | Approximately 100 days | 400-5000mcg daily. Common doses: 400-1000mcg daily. Folate (5-MTHF) form may be better than folic acid. (oral) |
| GABA | Not applicable | 100-1000mg daily. Common doses: 250-500mg before bed. Can be taken as needed or daily. (oral) |
| Glycine | Not applicable | 1-5g before bed. Common dose: 3g 30-60 minutes before sleep. Can be taken with magnesium. (oral) |
| Green Power Blend | Not applicable | 5-20g daily. Common doses: 10-15g daily. Mix with water or smoothies. Best taken in the morning. (oral) |
| HMB (Beta-Hydroxy Beta-Methylbutyrate) | Not applicable | 1-5g daily. Common dose: 3g daily, split into 2-3 doses. Best taken around workouts. (oral) |
| Horny Goat Weed (Icariin) | Not applicable | 250-1000mg daily. Common doses: 500-750mg daily. Look for standardized extracts (icariin content). (oral) |
| Iodine | Not applicable - mineral | 150-1000mcg daily. Common doses: 150-300mcg daily. RDA is 150mcg. Higher doses may be needed for some. (oral) |
| L-Arginine | Approximately 1-2 hours | 2-10g daily. Common doses: 3-6g daily. Often taken pre-workout. Higher doses (8-10g) for specific benefits. (oral) |
| L-Carnitine | Approximately 2-3 hours | 0.5-3g daily. Common doses: 1-2g daily. Can be taken pre-workout or with meals. (oral) |
| L-Theanine | Approximately 2-3 hours | 100-500mg daily. Common doses: 200-400mg daily. Can be taken in morning or before bed. (oral) |
| Maca Root | Not applicable | 1-6g daily. Common doses: 2-3g daily. Best taken with meals. Look for gelatinized maca for better digestion. (oral) |
| Magnesium | Not applicable - mineral | 200-600mg daily. Common doses: 300-400mg daily. Higher doses (600-800mg) may cause loose stools. (oral) |
| Magnesium Glycinate | Not applicable - mineral | 200-600mg daily (elemental magnesium). Common doses: 300-400mg before bed. (oral) |
| Magnesium L-Threonate | Not applicable - mineral | 144-600mg daily (elemental magnesium). Common doses: 200-400mg daily. Best taken before bed. (oral) |
| Melatonin | Approximately 30-60 minutes | 0.5-10mg daily. Common doses: 1-3mg before bed. Start with lower doses (0.5-1mg). (oral) |
| Nattokinase | Approximately 3-4 hours | 1000-6000 FU (Fibrinolytic Units) or 1000-6000mg daily. Common doses: 2000-4000 FU daily. Best taken on empty stomach. (oral) |
| Nicotinamide Riboside (NR) | Approximately 1-2 hours | 125-1000mg daily. Common doses: 250-500mg daily. (oral) |
| NMN (Nicotinamide Mononucleotide) | Approximately 1-2 hours | 125-1000mg daily. Common doses: 250-500mg daily. Higher doses (750-1000mg) for intensive protocols. (oral) |
| Omega-3 (Fish Oil) | Not applicable | 1-5g daily. Common doses: 2-3g daily. Look for high EPA/DHA content (at least 1g combined). (oral) |
| Panax Ginseng | Not applicable | 200-1000mg daily. Common doses: 400-600mg daily. Look for standardized extracts (ginsenosides). (oral) |
| Quercetin | Approximately 3-4 hours | 250-1500mg daily. Common doses: 500-1000mg daily. Often taken with resveratrol. (oral) |
| Resveratrol | Approximately 2-4 hours | 100-1000mg daily. Common doses: 250-500mg daily. Best taken with fat for absorption. (oral) |
| Saw Palmetto | Not applicable | 160-960mg daily. Common doses: 320-640mg daily. Look for standardized extracts. (oral) |
| Selenium | Not applicable - mineral | 50-400mcg daily. Common doses: 100-200mcg daily. Don't exceed 400mcg daily. (oral) |
| Shilajit | Not applicable | 250-1000mg daily. Common dose: 500mg daily. Best taken with meals. (oral) |
| Stinging Nettle Root | Not applicable | 300-1200mg daily. Common doses: 600-900mg daily. Best taken with meals. (oral) |
| Taurine | Not applicable | 1-5g daily. Common doses: 2-3g daily. Can be taken with meals or pre-workout. (oral) |
| Thiamine (Vitamin B1) | Approximately 9-18 days | 10-200mg daily. Common doses: 25-100mg daily. Best taken with meals. (oral) |
| Tongkat Ali (Eurycoma Longifolia) | Not applicable | 100-600mg daily. Common doses: 200-400mg daily. Look for standardized extracts (1% eurypeptides). (oral) |
| Tribulus Terrestris | Not applicable | 250-1500mg daily. Common doses: 500-1000mg daily. Look for standardized extracts (40% saponins). (oral) |
| Ubiquinol | Approximately 33 hours | 50-300mg daily. Common dose: 100-200mg daily. More bioavailable than ubiquinone. (oral) |
| Vitamin B12 | Approximately 6 days | 100-5000mcg daily. Common doses: 500-1000mcg daily. Sublingual or methylcobalamin forms may be better absorbed. (oral) |
| Vitamin B6 | Approximately 15-20 days | 10-100mg daily. Common doses: 25-50mg daily. Best taken with meals. (oral) |
| Vitamin C | Approximately 30 minutes | 500mg-5g daily. Common doses: 1-2g daily. Higher doses (3-5g) for immune support or during illness. (oral) |
| Vitamin D3 | Approximately 2-3 weeks | 1000-5000 IU daily. Many TRT users take 2000-4000 IU daily. Higher doses (5000-10000 IU) may be needed for deficiency correction.… |
| Vitamin E | Approximately 2-3 days | 100-800 IU daily. Common doses: 200-400 IU daily. Best taken with meals containing fat. (oral) |
| Vitamin K2 (MK-4) | Approximately 1-2 hours | 50-300mcg daily. Common dose: 100-200mcg daily. Often taken with Vitamin D3. (oral) |
| Vitamin K2 (MK-7) | Approximately 3 days (much longer than MK-4) | 50-300mcg daily. Common dose: 100-200mcg daily. Longer-acting than MK-4. (oral) |
| Zinc | Not applicable - mineral | 10-30mg daily. TRT users often take 15-25mg daily. Higher doses (30-50mg) may be used short-term but can cause copper deficiency.… |
Every row in the index above carries a half-life and a “typical reported dose”. Both are descriptive: they summarise what is commonly reported for a compound in the literature and in clinical practice, and neither is a recommendation for you. A dose is set by a licensed prescriber against your bloodwork, your history and your goal. What the library is good for is knowing what a compound is, roughly what scale of dose is normal, and how often it usually needs giving.
Three things determine whether a number on this page transfers to your situation at all:
Half-life is the time for blood levels to fall by half. It is the single most useful number in the index because it answers the question people usually ask second: how often. The spread across this library is nearly four orders of magnitude.
| Compound | Half-life | What that implies |
|---|---|---|
| Ipamorelin | ~2 hours | Daily or twice daily. A weekly schedule would leave almost no exposure. |
| BPC-157 | 4–6 hours | Daily, often split into two doses. |
| Testosterone propionate | ~19–20 hours | Every other day to keep levels even. |
| Testosterone enanthate | ~4.5 days | Once or twice weekly. |
| Testosterone cypionate | ~3.8 days | Once or twice weekly; the twice-weekly split is about smoothing peaks, not total dose. |
| Semaglutide | ~1 week | Weekly, and dose changes take weeks to show their full effect. |
| Retatrutide | ~6–8 days | Weekly. |
| Testosterone undecanoate | ~20–34 days | Every 10 to 14 weeks, and a mistake takes months to clear. |
Half-lives as listed in the library above. The practical consequence of a long half-life cuts both ways: fewer injections, but slower feedback and a much longer wait for a change to settle. The half-life calculator plots the curve for a given compound and interval, and the unit converter interprets the bloodwork you use to check it.
92 of the 217 entries carry reconstitution guidance, which is the tell that they ship as a lyophilised powder rather than a ready-made solution. That group is almost entirely the peptides: they arrive as a dry cake in a vial, you add bacteriostatic water, and the concentration you end up with is whatever you chose when you added it. This is the step that produces most dosing errors, because the same 5 mg vial can be 1 mg/mL or 5 mg/mL depending on how much water went in, and the syringe volume changes accordingly.
The index is grouped the same way the app is. Class is a rough functional grouping rather than a pharmacological taxonomy – several compounds could sit in two of them.
| Class | Count | What it covers |
|---|---|---|
| Vitamins & supplements | 58 | The largest group and the least exotic: micronutrients, minerals and common oral supplements, most of which interact with the rest of a protocol more than people expect. |
| Growth & recovery peptides | 41 | Growth-hormone secretagogues and repair peptides – ipamorelin, CJC-1295, BPC-157, TB-500, somatropin. |
| Cardiovascular & metabolic | 40 | Compounds affecting lipids, blood pressure, glucose handling and haematocrit – the side of a protocol that bloodwork catches first. |
| TRT & testosterone | 20 | Testosterone esters and the ancillaries that go with them: aromatase inhibitors, hCG, SERMs. |
| Longevity | 15 | Compounds studied for ageing and cellular repair, including NAD+ and the bioregulator peptides. |
| Cognitive | 13 | Nootropic peptides and racetams – Semax and Selank, noopept, cerebrolysin. |
| GLP-1 & weight management | 12 | The incretin agonists: semaglutide, tirzepatide, retatrutide, cagrilintide. See the GLP-1 hub. |
| Fat loss | 8 | Non-incretin fat-loss compounds, including fragment 176–191 and 5-amino-1MQ. |
| Specialty | 7 | Everything with no natural home: PT-141, oxytocin, melanotan and its Melanotan II variant. |
Anabolic steroids are documented separately, since the questions people ask about them are different: see the anabolic compound guides for trenbolone, primobolan, masteron, equipoise and the rest, and the cycle tracking guide for how to log one.
It is an educational reference built from published pharmacology and commonly reported protocols. It is not a prescription, not a supplier, and not a claim that any of these compounds is safe or appropriate for you. A large share of the entries here are not approved for the use people put them to, and several are research chemicals with no human dosing standard at all – the cards say so rather than omitting them, because “this is not established” is itself the useful information.
Where a compound is prescription-only, the right sequence is a conversation with a prescriber and bloodwork, not a dose from a table. Where one is not, the honest position is that the evidence base is usually thinner than the marketing around it. OptiPin exists to track what you and your prescriber decide on, not to decide it.
217, across nine classes: 58 vitamins and supplements, 41 growth and recovery peptides, 40 cardiovascular and metabolic, 20 TRT and testosterone, 15 longevity, 13 cognitive, 13 GLP-1, 9 fat loss and 8 specialty. Every one carries a half-life, typical reported dosing, common uses, side effects and warnings, and 92 of them carry reconstitution guidance. The app tracks all of them; this page is the same library in reference form.
No. It is a summary of what is commonly reported for that compound, given so you can tell a microgram compound from a milligram one and sanity-check what you have been told. Your dose comes from a licensed prescriber working from your bloodwork. Nothing on this page is medical advice.
It sets the interval, not the amount. A short half-life means levels fall quickly between injections, so the compound is usually given daily or more often – ipamorelin at about 2 hours is dosed daily. A long half-life means the opposite: testosterone undecanoate at 20 to 34 days is given every 10 to 14 weeks. The practical trade is that long-acting compounds need fewer injections but take months to correct if the dose is wrong.
Mostly the peptides – 92 of the 217 entries here. They ship as a freeze-dried powder and you add bacteriostatic water before use, which means you choose the final concentration. Get that step wrong and every dose afterwards is wrong by the same factor, so it is worth running through the reconstitution calculator rather than doing it in your head.
No. The full index on this page is free, needs no account, and the calculators linked from it are too. The app adds the part a table cannot do: logging what you actually took, projecting blood levels from your own bloodwork, and warning you before a vial runs out.
It varies by compound and by country. Most cards carry a status line saying which; where one is absent, assume nothing and check the label in your own country. Several entries are approved medicines used off-label, several are prescription-only in some countries and not others, and several are research chemicals with no approved human use anywhere. Approval status is not the same as safety, and neither is the same as whether something is appropriate for you.
It is regenerated from the same data file the app ships, so the page and the app never disagree. New compounds and corrections land here when they land in the app.
Published pharmacokinetic data where it exists, and commonly reported clinical or community protocols where it does not – which is the case for a fair number of the research peptides. Where a figure is an estimate rather than a measured value, the individual card says so. Treat a half-life with a wide range as exactly that: a range.