OptiPin
Humanin: uses, dosing & the facts
A mitochondrial-derived peptide (MDP) that protects cells from apoptosis and supports cellular longevity. Naturally produced in mitochondria and plays a role in anti-aging. This is an evidence-graded reference — what it is, what it's used for, typical reported dosing, half-life, side effects, and how to track it. It is educational, not medical advice or a recommendation to use a research compound.
- • Humanin — Longevity. A mitochondrial-derived peptide (MDP) that protects cells from apoptosis and supports cellular longevity.
- • Commonly used for anti-aging and longevity, cellular protection, neuroprotection.
- • Half-life: Approximately 2-3 hours.
- • Status: Research use only · not FDA-approved — an educational reference, not a dose protocol or sourcing advice.
What Humanin is
A mitochondrial-derived peptide (MDP) that protects cells from apoptosis and supports cellular longevity. Naturally produced in mitochondria and plays a role in anti-aging.
What Humanin is used for
- • Anti-aging and longevity
- • Cellular protection
- • Neuroprotection
- • Cardiovascular health
- • Apoptosis prevention
- • Metabolic health
These are reported/community uses, not proven clinical outcomes. Most research peptides have limited human trial data behind such claims.
Typical reported dosing
| Injectable | 1-10mg injected subcutaneously 2-3 times per week |
Presented as commonly-reported patterns for information only — not a dose recommendation. Humanin dosing is a decision for a qualified clinician.
Reconstitution
Reconstitute 5-10mg vial with 2mL bacteriostatic water. 1mg = varies by vial size. The arithmetic is the same for any peptide: concentration = vial mg ÷ water mL, and on a U-100 syringe 100 units = 1 mL. Compute your own vial with the reconstitution calculator.
Half-life & cycling
Half-life: Approximately 2-3 hours. Half-life drives dosing frequency and how quickly the compound clears — see it plotted on the half-life visualizer.
Cycling
Typical cycles: 8-12 weeks on, 4-6 weeks off. Can be used continuously with breaks. Most effective for longevity protocols.
Side effects & warnings
- • Generally well-tolerated
- • Minimal side effects reported
- • Mild injection site reactions possible
Research use only. Mitochondrial peptide with anti-aging potential. Expensive but may have significant longevity benefits. Newer research peptide with growing evidence.
Tracking Humanin in OptiPin
If you're tracking a Humanin protocol, OptiPin logs each dose with reminders and site rotation, charts the outcome you care about over your dose timeline, keeps per-vial inventory with runout warnings, and (where relevant) does the reconstitution math — all on-device, no account.
Log doses, outcomes & vials in OptiPin
Reminders, outcome-over-dose charts, vial runout warnings, and built-in reconstitution math — all on-device.
Download on the App StoreFAQ
What is Humanin?
A mitochondrial-derived peptide (MDP) that protects cells from apoptosis and supports cellular longevity. Naturally produced in mitochondria and plays a role in anti-aging.
What is Humanin used for?
Commonly discussed uses include: anti-aging and longevity, cellular protection, neuroprotection, cardiovascular health, apoptosis prevention, metabolic health. These are reported uses, not proven outcomes or a recommendation.
How is Humanin dosed?
Commonly reported dosing: Injectable — 1-10mg injected subcutaneously 2-3 times per week. This reflects patterns discussed in the community and is presented for information only, not as a dose recommendation — Humanin is not an approved medicine and dosing should involve a qualified clinician.
How do you reconstitute Humanin?
Reconstitute 5-10mg vial with 2mL bacteriostatic water. 1mg = varies by vial size. On a U-100 syringe, 100 units = 1 mL. Concentrations vary by vial, so compute from your own vial with a reconstitution calculator.
What is Humanin's half-life?
Approximately 2-3 hours. Half-life shapes how often it is dosed and how quickly it clears.
What are Humanin's side effects?
Reported effects include: generally well-tolerated, minimal side effects reported, mild injection site reactions possible. Because it is a research compound, its safety profile is not fully characterized; discuss risks with a clinician.
Evidence & further reading
- Search the peer-reviewed literature for Humanin on PubMed (entry point to the primary evidence base, not a specific citation).
- Humanin on ClinicalTrials.gov — registered human trials, if any.
- US FDA / 503A compounding status of research peptides (2026).
- OptiPin peptides guide — categories, evidence grading, and how to run a protocol honestly.
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