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Humanin: calculator, dosing & the facts
A mitochondrial-derived peptide (MDP) that protects cells from apoptosis and supports cellular longevity. Naturally produced in mitochondria and plays a role in anti-aging. This is an evidence-graded reference – what it is, what it's used for, typical reported dosing, half-life, side effects, and how to track it. It is educational, not medical advice or a recommendation to use a research compound.
- • Humanin – Longevity. A mitochondrial-derived peptide (MDP) that protects cells from apoptosis and supports cellular longevity.
- • Commonly used for anti-aging and longevity, cellular protection, neuroprotection.
- • Half-life: Approximately 2–3 hours.
- • Status: Research use only · not FDA-approved – an educational reference, not a dose protocol or sourcing advice.
Humanin calculator
Vial, water and dose in, syringe units out. Runs in your browser; nothing is sent anywhere.
Arithmetic only. The starting figures are the worked example in the reconstitution note on this page, not a dose recommendation. A U-40 syringe reads differently – see the syringe units chart. For a reusable pen, use the peptide pen calculator.
What Humanin is
A mitochondrial-derived peptide (MDP) that protects cells from apoptosis and supports cellular longevity. Naturally produced in mitochondria and plays a role in anti-aging.
What Humanin is used for
- • Anti-aging and longevity
- • Cellular protection
- • Neuroprotection
- • Cardiovascular health
- • Apoptosis prevention
- • Metabolic health
These are reported/community uses, not proven clinical outcomes. Most research peptides have limited human trial data behind such claims.
Typical reported dosing
| Injectable | 1–10mg injected subcutaneously 2–3 times per week |
Presented as commonly-reported patterns for information only – not a dose recommendation. Humanin dosing is a decision for a qualified clinician.
Reconstitution
Reconstitute 5–10mg vial with 2mL bacteriostatic water. 1mg = varies by vial size. The arithmetic is the same for any peptide: concentration = vial mg ÷ water mL, and on a U-100 syringe 100 units = 1 mL. Compute your own vial with the calculator at the top of this page.
Humanin dose-to-units chart
| Vial + water | Concentration | 1 unit holds | 1 mg |
|---|---|---|---|
| 5 mg + 2 mL | 2.5 mg/mL | 25 mcg | 40 u |
| 10 mg + 2 mL | 5 mg/mL | 50 mcg | 20 u |
Units on a U-100 insulin syringe, where 100 units = 1 mL. Red means under 5 units (a one-unit misread is a 20% dose error or worse) or over 100 (more than a 1 mL syringe holds). The dose columns are the worked examples in the reconstitution note above, shown as arithmetic, not as a recommendation.
Half-life & cycling
Half-life: Approximately 2–3 hours. Half-life drives dosing frequency and how quickly the compound clears – see it plotted on the Humanin half-life calculator.
Cycling
Typical cycles: 8–12 weeks on, 4–6 weeks off. Can be used continuously with breaks. Most effective for longevity protocols.
Side effects & warnings
- an injection site that turns red, hot or hard, spreads, weeps, or comes with a fever – same-day medical care – research-grade material carries no sterility guarantee, so abscess and cellulitis are the documented consequence
- swelling of the lips, tongue or throat, trouble breathing, or widespread hives after a dose – emergency care
- • Generally well-tolerated
- • Minimal side effects reported
- • Mild injection site reactions possible
Research use only. Mitochondrial peptide with anti-aging potential. Expensive but may have significant longevity benefits. Newer research peptide with growing evidence.
Tracking Humanin in OptiPin
If you're tracking a Humanin protocol, OptiPin logs each dose with reminders and site rotation, charts the outcome you care about over your dose timeline, keeps per-vial inventory with runout warnings, and (where relevant) does the reconstitution math – all on-device, no account.
Log doses, outcomes & vials in OptiPin
Reminders, outcome-over-dose charts, vial runout warnings, and built-in reconstitution math – all on-device.
Download on the App StoreFAQ
What is Humanin?
A mitochondrial-derived peptide (MDP) that protects cells from apoptosis and supports cellular longevity. Naturally produced in mitochondria and plays a role in anti-aging.
How many units is 1 mg of Humanin?
On a U-100 insulin syringe, from a 5 mg vial with 2 mL of water it is 40 units (0.4 mL); from a 10 mg vial with 2 mL of water it is 20 units (0.2 mL). The answer depends entirely on how much water went into the vial, so check your own vial with the calculator on this page. This is arithmetic, not a dose recommendation.
What is Humanin used for?
Commonly discussed uses include: anti-aging and longevity, cellular protection, neuroprotection, cardiovascular health, apoptosis prevention, metabolic health. These are reported uses, not proven outcomes or a recommendation.
How is Humanin dosed?
Commonly reported dosing: Injectable – 1–10mg injected subcutaneously 2–3 times per week. This reflects patterns discussed in the community and is presented for information only, not as a dose recommendation – Humanin is not an approved medicine and dosing should involve a qualified clinician.
How do you reconstitute Humanin?
Reconstitute 5–10mg vial with 2mL bacteriostatic water. 1mg = varies by vial size. On a U-100 syringe, 100 units = 1 mL. Concentrations vary by vial, so compute from your own vial with a reconstitution calculator.
What is Humanin's half-life?
Approximately 2–3 hours. Half-life shapes how often it is dosed and how quickly it clears.
What are Humanin's side effects?
Reported effects include: generally well-tolerated, minimal side effects reported, mild injection site reactions possible. Because it is a research compound, its safety profile is not fully characterized; discuss risks with a clinician.
Evidence & further reading
- Search the peer-reviewed literature for Humanin on PubMed (entry point to the primary evidence base, not a specific citation).
- Humanin on ClinicalTrials.gov – registered human trials, if any.
- US FDA / 503A compounding status of research peptides (2026).
- OptiPin peptides guide – categories, evidence grading, and how to run a protocol honestly.
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