OptiPin
SS-31 (Elamipretide): uses, dosing & the facts
A mitochondrial-targeted peptide that protects mitochondria from damage and supports cellular energy production. Currently in clinical trials for various mitochondrial disorders. This is an evidence-graded reference – what it is, what it's used for, typical reported dosing, half-life, side effects, and how to track it. It is educational, not medical advice or a recommendation to use a research compound.
- • SS-31 (Elamipretide) – Longevity. A mitochondrial-targeted peptide that protects mitochondria from damage and supports cellular energy production.
- • Commonly used for mitochondrial protection, cellular energy support, anti-aging and longevity.
- • Half-life: Approximately 2–3 hours.
- • Status: Research use only · not FDA-approved – an educational reference, not a dose protocol or sourcing advice.
What SS-31 (Elamipretide) is
A mitochondrial-targeted peptide that protects mitochondria from damage and supports cellular energy production. Currently in clinical trials for various mitochondrial disorders.
What SS-31 (Elamipretide) is used for
- • Mitochondrial protection
- • Cellular energy support
- • Anti-aging and longevity
- • Neuroprotection
- • Cardiovascular health
- • Fatigue reduction
These are reported/community uses, not proven clinical outcomes. Most research peptides have limited human trial data behind such claims.
Typical reported dosing
| Injectable | 1–10mg injected subcutaneously daily or every other day |
Presented as commonly-reported patterns for information only – not a dose recommendation. SS-31 (Elamipretide) dosing is a decision for a qualified clinician.
Reconstitution
Reconstitute 5–10mg vial with 2mL bacteriostatic water. 1mg = varies by vial size. The arithmetic is the same for any peptide: concentration = vial mg ÷ water mL, and on a U-100 syringe 100 units = 1 mL. Compute your own vial with the reconstitution calculator.
Half-life & cycling
Half-life: Approximately 2–3 hours. Half-life drives dosing frequency and how quickly the compound clears – see it plotted on the SS-31 (Elamipretide) half-life calculator.
Cycling
Typical cycles: 8–12 weeks on, 4–6 weeks off. Can be used continuously with breaks. Most effective for mitochondrial health protocols.
Side effects & warnings
- an injection site that turns red, hot or hard, spreads, weeps, or comes with a fever – same-day medical care – research-grade material carries no sterility guarantee, so abscess and cellulitis are the documented consequence
- swelling of the lips, tongue or throat, trouble breathing, or widespread hives after a dose – emergency care
- • Generally well-tolerated
- • Minimal side effects reported
- • Mild injection site reactions possible
Research use only. Mitochondrial-targeted peptide with significant potential. Currently in clinical trials for various conditions. Expensive but may have significant benefits for energy and longevity. Very promising research peptide.
Tracking SS-31 (Elamipretide) in OptiPin
If you're tracking a SS-31 (Elamipretide) protocol, OptiPin logs each dose with reminders and site rotation, charts the outcome you care about over your dose timeline, keeps per-vial inventory with runout warnings, and (where relevant) does the reconstitution math – all on-device, no account.
Log doses, outcomes & vials in OptiPin
Reminders, outcome-over-dose charts, vial runout warnings, and built-in reconstitution math – all on-device.
Download on the App StoreFAQ
What is SS-31 (Elamipretide)?
A mitochondrial-targeted peptide that protects mitochondria from damage and supports cellular energy production. Currently in clinical trials for various mitochondrial disorders.
What is SS-31 (Elamipretide) used for?
Commonly discussed uses include: mitochondrial protection, cellular energy support, anti-aging and longevity, neuroprotection, cardiovascular health, fatigue reduction. These are reported uses, not proven outcomes or a recommendation.
How is SS-31 (Elamipretide) dosed?
Commonly reported dosing: Injectable – 1–10mg injected subcutaneously daily or every other day. This reflects patterns discussed in the community and is presented for information only, not as a dose recommendation – SS-31 (Elamipretide) is not an approved medicine and dosing should involve a qualified clinician.
How do you reconstitute SS-31 (Elamipretide)?
Reconstitute 5–10mg vial with 2mL bacteriostatic water. 1mg = varies by vial size. On a U-100 syringe, 100 units = 1 mL. Concentrations vary by vial, so compute from your own vial with a reconstitution calculator.
What is SS-31 (Elamipretide)'s half-life?
Approximately 2–3 hours. Half-life shapes how often it is dosed and how quickly it clears.
What are SS-31 (Elamipretide)'s side effects?
Reported effects include: generally well-tolerated, minimal side effects reported, mild injection site reactions possible. Because it is a research compound, its safety profile is not fully characterized; discuss risks with a clinician.
Evidence & further reading
- Search the peer-reviewed literature for SS-31 (Elamipretide) on PubMed (entry point to the primary evidence base, not a specific citation).
- SS-31 (Elamipretide) on ClinicalTrials.gov – registered human trials, if any.
- US FDA / 503A compounding status of research peptides (2026).
- OptiPin peptides guide – categories, evidence grading, and how to run a protocol honestly.
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