Skip to content
OptiPin app icon OptiPin
Download

Melanotan: uses, dosing & the facts

A peptide that stimulates melanogenesis (tanning) and may increase libido. Available in two forms: Melanotan 1 and Melanotan 2. Most commonly refers to MT-2. This is an evidence-graded reference – what it is, what it's used for, typical reported dosing, half-life, side effects, and how to track it. It is educational, not medical advice or a recommendation to use a research compound.

Status
Research use only · not FDA-approved. Reported dosing below reflects community-discussed patterns, presented for information only – not a dose recommendation. For the US regulatory picture on research peptides, see the 2026 FDA compounding status.
Class
Specialty
Used for
Tanning without UV exposure
Half-life
Approximately 36 hours
Status
Research use only
TL;DR

What Melanotan is

A peptide that stimulates melanogenesis (tanning) and may increase libido. Available in two forms: Melanotan 1 and Melanotan 2. Most commonly refers to MT-2.

What Melanotan is used for

These are reported/community uses, not proven clinical outcomes. Most research peptides have limited human trial data behind such claims.

Typical reported dosing

Injectable50–100mcg subcutaneously daily for loading phase, then 250–500mcg weekly for maintenance
Nasal200–1000mcg nasally per dose. Higher amounts than injectable are typical because nasal absorption is lower.

Presented as commonly-reported patterns for information only – not a dose recommendation. Melanotan dosing is a decision for a qualified clinician.

Reconstitution

Reconstitute with bacteriostatic water. Gradually expose to UV after loading phase. The arithmetic is the same for any peptide: concentration = vial mg ÷ water mL, and on a U-100 syringe 100 units = 1 mL. Compute your own vial with the reconstitution calculator.

Half-life & cycling

Half-life: Approximately 36 hours. Half-life drives dosing frequency and how quickly the compound clears – see it plotted on the Melanotan half-life calculator.

Cycling

Loading phase: 10–14 days. Maintenance: 1–2x per week. Keep out of sun during loading phase.

Side effects & warnings

Stop and get medical help if any of these happen. This is not the general "talk to a clinician before you start" line further down; these are the things that need attention on the day they appear, whatever you decided about Melanotan.
  • an injection site that turns red, hot or hard, spreads, weeps, or comes with a fever – same-day medical care – research-grade material carries no sterility guarantee, so abscess and cellulitis are the documented consequence
  • swelling of the lips, tongue or throat, trouble breathing, or widespread hives after a dose – emergency care
  • an erection lasting more than four hours – emergency care – priapism causes permanent damage untreated
  • a mole that is new, changing, or bleeding – a dermatology review before any further dosing

Very effective tanning agent but significant side effects. Can cause severe nausea. Must gradually introduce sun exposure. Can cause libido increases. Research use only.

Not a prescription, a dose, or a sourcing guide. Melanotan is a research compound; safety and efficacy in humans are not fully established, and research-grade material has no guarantee of purity, sterility, or stated strength. OptiPin is a tracking tool and does not recommend using research chemicals. Discuss any peptide with a qualified clinician.

Tracking Melanotan in OptiPin

If you're tracking a Melanotan protocol, OptiPin logs each dose with reminders and site rotation, charts the outcome you care about over your dose timeline, keeps per-vial inventory with runout warnings, and (where relevant) does the reconstitution math – all on-device, no account.

Track it properly

Log doses, outcomes & vials in OptiPin

Reminders, outcome-over-dose charts, vial runout warnings, and built-in reconstitution math – all on-device.

Download on the App Store

FAQ

What is Melanotan?

A peptide that stimulates melanogenesis (tanning) and may increase libido. Available in two forms: Melanotan 1 and Melanotan 2. Most commonly refers to MT-2.

What is Melanotan used for?

Commonly discussed uses include: tanning without uv exposure, libido enhancement, appetite suppression (mt-2), skin pigmentation, bodybuilding tanning, increased confidence with darker skin. These are reported uses, not proven outcomes or a recommendation.

How is Melanotan dosed?

Commonly reported dosing: Injectable – 50–100mcg subcutaneously daily for loading phase, then 250–500mcg weekly for maintenance; Nasal – 200–1000mcg nasally per dose. Higher amounts than injectable are typical because nasal absorption is lower.. This reflects patterns discussed in the community and is presented for information only, not as a dose recommendation – Melanotan is not an approved medicine and dosing should involve a qualified clinician.

How do you reconstitute Melanotan?

Reconstitute with bacteriostatic water. Gradually expose to UV after loading phase. On a U-100 syringe, 100 units = 1 mL. Concentrations vary by vial, so compute from your own vial with a reconstitution calculator.

What is Melanotan's half-life?

Approximately 36 hours. Half-life shapes how often it is dosed and how quickly it clears.

What are Melanotan's side effects?

Reported effects include: nausea and appetite suppression, flushing, freckles and moles darkening, spontaneous erections in men, yawning and lethargy, nausea. Because it is a research compound, its safety profile is not fully characterized; discuss risks with a clinician.

Educational only, not medical advice. Melanotan is a research compound and is not an approved medicine for the uses described. OptiPin is a tracking tool and does not provide dosing or treatment advice. Discuss any peptide with a qualified clinician.

Evidence & further reading

Related

Oxytocin · Argireline · DSIP · Kisspeptin · PT-141 · melanotan-ii · Reconstitution calculator · All peptides