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IGF-1 LR3: calculator, dosing & the facts
Insulin-like Growth Factor 1 Long R3, a long-acting form of IGF-1 with increased potency and duration. Powerful anabolic and metabolic effects. This is an evidence-graded reference – what it is, what it's used for, typical reported dosing, half-life, side effects, and how to track it. It is educational, not medical advice or a recommendation to use a research compound.
- • IGF-1 LR3 – Growth factor. Insulin-like Growth Factor 1 Long R3, a long-acting form of IGF-1 with increased potency and duration.
- • Commonly used for muscle growth and size, recovery enhancement, fat loss.
- • Half-life: Approximately 20–30 hours.
- • Status: Research use only · not FDA-approved – an educational reference, not a dose protocol or sourcing advice.
IGF-1 LR3 calculator
Vial, water and dose in, syringe units out. Runs in your browser; nothing is sent anywhere.
Arithmetic only. The starting figures are the worked example in the reconstitution note on this page, not a dose recommendation. A U-40 syringe reads differently – see the syringe units chart. For a reusable pen, use the peptide pen calculator.
What IGF-1 LR3 is
Insulin-like Growth Factor 1 Long R3, a long-acting form of IGF-1 with increased potency and duration. Powerful anabolic and metabolic effects.
What IGF-1 LR3 is used for
- • Muscle growth and size
- • Recovery enhancement
- • Fat loss
- • Joint and tendon healing
- • Skin and hair health
- • Athletic performance
These are reported/community uses, not proven clinical outcomes. Most research peptides have limited human trial data behind such claims.
Typical reported dosing
| Injectable | Beginners: 20–50mcg daily post-workout. Intermediate/Advanced: 50–100mcg daily. Some split doses AM/PM. Usually taken immediately after training to maximize muscle growth and recovery. |
Presented as commonly-reported patterns for information only – not a dose recommendation. IGF-1 LR3 dosing is a decision for a qualified clinician.
Reconstitution
Reconstitute 1mg vial with 2mL bacteriostatic water. 50mcg = 10 units. The arithmetic is the same for any peptide: concentration = vial mg ÷ water mL, and on a U-100 syringe 100 units = 1 mL. Compute your own vial with the calculator at the top of this page.
IGF-1 LR3 dose-to-units chart
| Vial + water | Concentration | 1 unit holds | 50 mcg |
|---|---|---|---|
| 1 mg + 2 mL | 0.5 mg/mL | 5 mcg | 10 u |
Units on a U-100 insulin syringe, where 100 units = 1 mL. Red means under 5 units (a one-unit misread is a 20% dose error or worse) or over 100 (more than a 1 mL syringe holds). The dose columns are the worked examples in the reconstitution note above, shown as arithmetic, not as a recommendation.
Half-life & cycling
Half-life: Approximately 20–30 hours. Half-life drives dosing frequency and how quickly the compound clears – see it plotted on the IGF-1 LR3 half-life calculator.
Cycling
Typical cycles: 4–8 weeks on, 4–6 weeks off. Very potent and expensive.
Side effects & warnings
- an injection site that turns red, hot or hard, spreads, weeps, or comes with a fever – same-day medical care – research-grade material carries no sterility guarantee, so abscess and cellulitis are the documented consequence
- swelling of the lips, tongue or throat, trouble breathing, or widespread hives after a dose – emergency care
- new numbness or tingling in the hands, or hands and ankles that stay swollen – stop and get assessed – these are the classic signs of too much growth hormone signalling
- unusual thirst, or passing much more urine than normal – a blood-glucose check, since GH secretagogues raise it
- • Hypoglycemia (low blood sugar) – very important
- • Possible organ growth with long-term use
- • Water retention
- • Fatigue from low blood sugar
- • Increased hunger
Can cause dangerous hypoglycemia. Must consume simple carbs after injection. Monitor blood sugar. Very expensive. Not for beginners. Higher doses raise the risk of hypoglycemia and receptor desensitization.
Tracking IGF-1 LR3 in OptiPin
If you're tracking a IGF-1 LR3 protocol, OptiPin logs each dose with reminders and site rotation, charts the outcome you care about over your dose timeline, keeps per-vial inventory with runout warnings, and (where relevant) does the reconstitution math – all on-device, no account.
Log doses, outcomes & vials in OptiPin
Reminders, outcome-over-dose charts, vial runout warnings, and built-in reconstitution math – all on-device.
Download on the App StoreFAQ
What is IGF-1 LR3?
Insulin-like Growth Factor 1 Long R3, a long-acting form of IGF-1 with increased potency and duration. Powerful anabolic and metabolic effects.
How many units is 50 mcg of IGF-1 LR3?
On a U-100 insulin syringe, from a 1 mg vial with 2 mL of water it is 10 units (0.1 mL). The answer depends entirely on how much water went into the vial, so check your own vial with the calculator on this page. This is arithmetic, not a dose recommendation.
What is IGF-1 LR3 used for?
Commonly discussed uses include: muscle growth and size, recovery enhancement, fat loss, joint and tendon healing, skin and hair health, athletic performance. These are reported uses, not proven outcomes or a recommendation.
How is IGF-1 LR3 dosed?
Commonly reported dosing: Injectable – Beginners: 20–50mcg daily post-workout. Intermediate/Advanced: 50–100mcg daily. Some split doses AM/PM. Usually taken immediately after training to maximize muscle growth and recovery.. This reflects patterns discussed in the community and is presented for information only, not as a dose recommendation – IGF-1 LR3 is not an approved medicine and dosing should involve a qualified clinician.
How do you reconstitute IGF-1 LR3?
Reconstitute 1mg vial with 2mL bacteriostatic water. 50mcg = 10 units. On a U-100 syringe, 100 units = 1 mL. Concentrations vary by vial, so compute from your own vial with a reconstitution calculator.
What is IGF-1 LR3's half-life?
Approximately 20–30 hours. Half-life shapes how often it is dosed and how quickly it clears.
What are IGF-1 LR3's side effects?
Reported effects include: hypoglycemia (low blood sugar) – very important, possible organ growth with long-term use, water retention, fatigue from low blood sugar, increased hunger. Because it is a research compound, its safety profile is not fully characterized; discuss risks with a clinician.
Evidence & further reading
- Search the peer-reviewed literature for IGF-1 LR3 on PubMed (entry point to the primary evidence base, not a specific citation).
- IGF-1 LR3 on ClinicalTrials.gov – registered human trials, if any.
- US FDA / 503A compounding status of research peptides (2026).
- OptiPin peptides guide – categories, evidence grading, and how to run a protocol honestly.
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